Changes of Activities of Oxygen Free Radical, Generating and Scavenging Enzymes in Rat Liver Induced by Scald Burn Injury

피부화상에 의한 간 조직의 oxygen free radical 생성계 효소와 해독계 효소의 활성변화

  • Kim Han-Soo (Department of Physical Therapy, Taegu Health College) ;
  • Cho Hyun-Gug (Department of Biology, Yeungnam University) ;
  • Kim Sang-Soo (Department of Physical Therapy, Taegu Health College) ;
  • Bae Ju-Han (Kyung-Hee Oriental Hospital) ;
  • Seo Hyun-Kyu (Department of Physical Therapy, College of Rehabilitation Science, Taegu University)
  • 김한수 (대구보건대학 물리치료과) ;
  • 조현국 (영남대학교 생물학과) ;
  • 김상수 (대구보건대학 물리치료과) ;
  • 배주한 (경희 한방병원) ;
  • 서현규 (대구대학교 재활과학대학원 물리치료)
  • Published : 1999.12.01

Abstract

The effects of scald bum Injury ($40-45\%$ of total body surface area), there were not inhalation and secondary infection, on the histological changes and the levels of oxygen free radical generating and scavenging enzymes have been determined in liver tissue of rat models. It was found that dermal epithelium was left out with edema of dermis layer and hydorpic swelling of hepatocytes, Burn injury increased liver weight (L.W./B.W.) and serum aspartate aminotransferase content (pThe data of this study suggest that liver damage Induced by scald burn injury leads to dysbalance of oxygen free radical generating and scavenging enzymes.

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