Korean Journal of Clinical Pharmacy (한국임상약학회지)
- Volume 9 Issue 1
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- Pages.27-34
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- 1999
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- 1226-6051(pISSN)
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- 2508-786X(eISSN)
The Evaluation of Therapeutic Control with Warfarin in Patients with Mechanical Heart Valve Prostheses
인공심장판막 환자를 대상으로 한 Warfarin 치료의 적정성 평가
- Im, Young Sun (Department of Pharmacy, Yonsei University Cardiovascular Center) ;
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Chang, Byung Chul
(Yonsei University Cardiovascular Center, Department of Chest Surgery Yonsei University College of Medicine) ;
- Suh, Ok Kyung (Graduate School of Clinical Pharmacy, Sookmyung Women's University) ;
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Lee, Suk Hyang
(Graduate School of Clinical Pharmacy, Sookmyung Women's University) ;
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Shin, Hyun Taek
(Graduate School of Clinical Pharmacy, Sookmyung Women's University)
- 임영선 (연세의료원 약제부) ;
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장병철
(연세대학교 의과대학 흉부외과부 교실) ;
- 서옥경 (숙명여자대학교 임상약학 대학원) ;
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이숙향
(숙명여자대학교 임상약학 대학원) ;
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신현택
(숙명여자대학교 임상약학 대학원)
- Published : 1999.05.01
Abstract
The goal of oral anticoagulation therapy with warfarin is to maintain INR values within the therapeutic range in order to prevent complications such as bleeding and thrombosis. The purposes of this study were to investigate the current level of anticoagulation control using INR values, to investigate the incidences of thromboembolism and bleeding complications, and to compare the effect of low intensity INR regimen with therapeutic range recommended by ACCP (American College of Chest Physician). Two hundred three patients with mechanical heart valve replacement done at Yonsei University Cardiovascular Center between January 1994 and December 1996 were selected and reviewed retrospectively. The target INR ranges of