The Effects of Oyo-Tang(五拗湯) on the Respiratory Patterns and Tracheal Tissues in Allergic Asthma

오요탕(五拗湯)이 알레르기 천식(喘息)의 호흡(呼吸) 양상(樣相)과 기관(氣管) 조직(組織)에 미치는 영향(影響)

  • Kwon, Soon-Ho (Division of Repiratory System, Dept. of Internal Medicine College of Oriental Medicine, Kyung Hee University) ;
  • Jung, Hee-Jae (Division of Repiratory System, Dept. of Internal Medicine College of Oriental Medicine, Kyung Hee University) ;
  • Jung, Sung-Ki (Division of Repiratory System, Dept. of Internal Medicine College of Oriental Medicine, Kyung Hee University) ;
  • Rhee, Hyung-Koo (Division of Repiratory System, Dept. of Internal Medicine College of Oriental Medicine, Kyung Hee University)
  • 권순호 (경희대학교 한의과대학 폐계내과학 교실) ;
  • 정희재 (경희대학교 한의과대학 폐계내과학 교실) ;
  • 정승기 (경희대학교 한의과대학 폐계내과학 교실) ;
  • 이형구 (경희대학교 한의과대학 폐계내과학 교실)
  • Published : 1999.06.30

Abstract

This study aimed to find out Oyo-Tang's effects on allergic asthma using the Egg-White Implant(EWI) method model recommended by Siqueira et al. Oyo-Tang has widely been prescribed and used in Oriental Medicine for controlling and curing of cough, nasal obstruction, pharyngeal pain and hoarseness. Previous studies have demonstrated that Oyo-Tang has analgesic, sedative, anticonvulsive, antitussive and antihistamine effects. But it was uncertain whether Oyo-Tang could inhibit the allergic reactions, to alleviate the symptoms of allergic asthma. With such aim. the respiratory patterns and eosinophil infiltration in the tracheal mucosa of rats with experimentally induced allergic asthma (using EWI method) were mainly observed. The results are as follows: 1. Oyo-Tang decreased the number of poor respiration with respect to control group (P<0.05) 2. Oyo-Tang decreased the number of eosinophils infiltrated in tracheal mucosa with respect control group (P<0.05). The above results demonstrate that Oyo-Tang has the inhibitory effects on the process allergic asthma and suggest that it could be used in relieving patients of the symptoms caused allergic asthma.

Keywords

References

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