대한한의학회지 (The Journal of Korean Medicine)

  • 제20권2호
  • /
  • Pages.63-74
  • /
  • 1999
  • /
  • 1010-0695(pISSN)
  • /
  • 2288-3339(eISSN)
대한한의학회 (The Society of Korean Medicine)
권호 표지

석문(石門)($CV_5$) 애구(艾灸)가 자성(雌性) 백서(白鼠)의 $3{\beta}-hydroxysteroid\;dehydrogenasa/{\Delta}^5-{\Delta}^4$ isomerase $(3{\beta}-HSD)$의 발현(發顯) 양상(樣相)에 미치는 영향(影響)

Effects of Moxibustion at the CV5(Serk-Moon) on the Expression of $3{\beta}-Hydroxysteroid\; dehydrogenasa/{\Delta}5-{\Delta}4$ isomerase $(3{\beta}-HSD)$ in Ovary of the Rats

  • 최영순 (원광대학교 한의과대학 경혈학교실) ;
  • 안성훈 (원광대학교 한의과대학 경혈학교실) ;
  • 구성태 (원광대학교 한의과대학 경혈학교실) ;
  • 이문호 (세명대학교 한의과대학 침구학교실) ;
  • 김경식 (원광대학교 한의과대학 경혈학교실) ;
  • 손인철 (원광대학교 한의과대학 경혈학교실)
  • Choi, Young-Sun (Dept. of Acupuncture and Moxibustion, School of Oriental Medicine, Wonkwang Univ.) ;
  • Ahn, Sung-Hun (Dept. of Acupuncture and Moxibustion, School of Oriental Medicine, Wonkwang Univ.) ;
  • Koo, Sung-Tae (Dept. of Acupuncture and Moxibustion, School of Oriental Medicine, Wonkwang Univ.) ;
  • Lee, Mun-Ho (Dept. of Acupuncture and Moxibustion, School of Oriental Medicine, Semyung Univ.) ;
  • Kim, Kyung-Sik (Dept. of Acupuncture and Moxibustion, School of Oriental Medicine, Wonkwang Univ.) ;
  • Sohn, In-Chul (Dept. of Acupuncture and Moxibustion, School of Oriental Medicine, Wonkwang Univ.)
  • 발행 : 1999.06.30
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초록

We demonstrated the moxibution on CV5(Serk-Moon) and CV3(Chung-Guk), as we have known contraceptive acupuncture point and pregnancy acupuncture point in oriental medcine, effected on concentration of progesteron and estrogen. As the reports, $3{\beta}-hydroxysteroid\;dehydrogenase/{\Delta}5-{\Delta}4$ isomerase $(3{\beta}-HSD)$ is an enzyme that has catalytic oxidation and isomerase reaction on steroidhormon synthase including progesteron and estrogen. So we observated the concentration and mass of $(3{\beta}-HSD)$ by immuno-chemicalstain, western blot and Enzyme-Linked Immunosorbent Assay in rat ovary. In results, we detected that the mass of $(3{\beta}-HSD)$ decreased significantly in moxibution treated group on CV5($p{\leq}0.05$) in rat ovary and proposed that the moxibution of CV5 make possible to contraception because of blocking estrogen synthesis by $(3{\beta}-HSD)$ decrease. But we didn't know moxibution effects exactly whether is biochemical reaction or thermal reaction on acupuncture point.

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참고문헌

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