대한한의학회지 (The Journal of Korean Medicine)

  • 제20권1호
  • /
  • Pages.161-171
  • /
  • 1999
  • /
  • 1010-0695(pISSN)
  • /
  • 2288-3339(eISSN)
대한한의학회 (The Society of Korean Medicine)
권호 표지

고려홍삼 복합방이 실험적 뇌경색에 미치는 영향

Effects of Complex formula including Korea Red Ginseng (CKRG) on Brain Ischemia Induced by Occlusion of Middle Cerebral Artery

  • 오상진 (충남대학교 생화학과) ;
  • 박일현 (충남대학교 생화학과) ;
  • 김성훈 (경희대학교 동서의학대학원)
  • 발행 : 1999.03.30
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초록

This study was performed to investigate the effect of complex formula(CKRG) consisting of Panax ginseng Radix rubra Koreana. Ganoderma, Cinnamomi Cortex, Glycyrrhizae Radix and Laminariae Thallus on brain ischemia and injury such as KCN-induced brain injury, forced brain ischemia, pulmonary thrombosis. The results were summarized as follows: 1. CKRG extracts showed a decrease of the duration of KCN-induced coma and showcd an increase in life expectancy. 2. CKRG extracts showed a decrease of neurologic grade in hind limb but did not affect neurologic grades in fore limb. Also. CKRG extracts showed a significant decrease of brain ischemic area and edema in MCA occlusion, 3. CKRG extracts showed a protective effect on pulmonary thrombosis induced by collagen and epinephrine. These data suggested that CKRG extracts could be applied to the protection of brain ischemia and injury.

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참고문헌

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