생약학회지 (Korean Journal of Pharmacognosy)
- 제30권4호
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- Pages.355-362
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- 1999
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- 0253-3073(pISSN)
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- 2288-9299(eISSN)
사람 말초혈액 단핵세포에서 녹두 렉틴의 사이토카인 생성효과
Effect of Mung Bean Lectin (MBL) on Cytokine Gene Expression from Human Peripheral Blood Mononuclear Cells
- 전경희 (영남대학교 이과대학) ;
- 안몽기 (영남대학교 의과대학 부속병원) ;
- 정수민 (영남대학교 약학대학) ;
- 최경민 (영남대학교 약학대학) ;
- 이승호 (영남대학교 약학대학) ;
- 정시련 (영남대학교 약학대학)
- Jeune, Kyung-Hee (College of Science, Yeungnam University) ;
- An, Mong-Gi (Yeungnam University Hospital) ;
- Jung, Su-Min (College of Pharmacy, Yeungnam University) ;
- Choi, Kyung-Min (College of Pharmacy, Yeungnam University) ;
- Lee, Seung-Ho (College of Pharmacy, Yeungnam University) ;
- Chung, See-Ryun (College of Pharmacy, Yeungnam University)
- 발행 : 1999.12.30
초록
New lectins have been isolated and purified from mung bean (Phaseolus radiatus) through physiological saline extraction, ammonium sulfate salt fractionation and column chromatographies. Ion exchanger were eluted by linear salt gradient and then further purified through gel filtration. Thus obtained lectin named as MBL. The gene expressions of 5 cytokines (IL-1, IL-2, IL-6,
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