생약학회지 (Korean Journal of Pharmacognosy)
- 제30권1호
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- Pages.25-33
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- 1999
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- 0253-3073(pISSN)
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- 2288-9299(eISSN)
잔나비걸상버섯 수용성물질의 항바이러스효과
Antiviral Activity of Water Soluble Substance from Elfvingia applanata
- Rym, Kyo-Hwan (College of Pharmacy, Chungbuk National University) ;
- Eo, Seong-Kug (College of Pharmacy, Chungbuk National University) ;
- Kim, Young-So (College of Pharmacy, Chungbuk National University) ;
- Lee, Chong-Kil (College of Pharmacy, Chungbuk National University) ;
- Han, Seong-Sun (College of Pharmacy, Chungbuk National University)
- 발행 : 1999.03.30
초록
In order to find less toxic antiviral agents from basidiomycetes, EA, the water soluble substance, was prepared from the carpophores of Elfvingia applanata (Pers.) Karst. EA was examined for antiviral activity against five strains of pathogenic viruses such as encephalomyocarditis virus (EMCV), vesicular stomatitis virus (VSV) Indiana and New Jersey strains, influenza A virus (Flu A), and varicella zoster virus (VZV) in vitro. Antiviral activity was evaluated by plaque reduction assay. Among five strains of viruses tested, EA exhibited the most potent antiviral activity against VSV Indiana strain with 50% effective concentration