Natural Product Sciences
- Volume 5 Issue 4
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- Pages.162-164
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- 1999
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- 1226-3907(pISSN)
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- 2288-9027(eISSN)
Anti-HIV Activity of Dehydroaltenusin- a Metabolite from a Streptomyces sp.
- Jabbar, Abdul (Laboratory of Natural Products, Faculty of Pharmacy, University of Dhaka) ;
- Shresta, Ajude Prashad (Laboratory of Natural Products, Faculty of Pharmacy, University of Dhaka) ;
- Hasan, Choudhury Mahmood (Laboratory of Natural Products, Faculty of Pharmacy, University of Dhaka) ;
- Rashid, Mohammad Abdur (Laboratory of Natural Products, Faculty of Pharmacy, University of Dhaka)
- Published : 1999.12.01
Abstract
Dehydroaltenusin (1) was isolated from the chloroform extract of the culture filtrate of a Streptomyces sp. and its structure was determined from spectral data as well as by comparison with published values. In an XTT-based in vitro anti-HIV assay, dehydroaltenusin effectively inhibited the cytopathic effects of HIV infection at a concentration of