Natural Product Sciences

  • 제5권1호
  • /
  • Pages.20-24
  • /
  • 1999
  • /
  • 1226-3907(pISSN)
  • /
  • 2288-9027(eISSN)
한국생약학회 (The Korean Society of Pharmacognosy)
권호 표지

Anti-emetic Principles of Alpinia katsumadai Hayata

  • Yang, Ye (Department of Pharmacognosy and Phytochemistry, Meiji Pharmaceutical University) ;
  • Kinoshita, Kaoru (Department of Pharmacognosy and Phytochemistry, Meiji Pharmaceutical University) ;
  • Koyama, Kiyotaka (Department of Pharmacognosy and Phytochemistry, Meiji Pharmaceutical University) ;
  • Takahashi, Kunio (Department of Pharmacognosy and Phytochemistry, Meiji Pharmaceutical University) ;
  • Tai, Takaaki (Kotaro Pharmaceutical Co. Ltd.) ;
  • Nunoura, Yoshiki (Kotaro Pharmaceutical Co. Ltd.) ;
  • Watanabe, Kazuo (Faculty of Pharmaceutical Sciences, Chiba University)
  • 발행 : 1999.03.01
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초록

Bioassay-guided fractionation of anti-emetic constituents of Alpinia katsumadai Hayata was performed. Nine compounds including one novel compound, (3R,5S)-trans-3,5-dihydroxy-1,7-diphenyl-1-heptene (9) were isolated from it. Among these compounds, four diarylheptanoids, one sesquiterpenoid and one flavonoid showed anti-emetic activity on copper sulfate induced-emesis in young chicks.

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