The Korean Journal of Physiology and Pharmacology
- 제3권4호
- /
- Pages.393-404
- /
- 1999
- /
- 1226-4512(pISSN)
- /
- 2093-3827(eISSN)
Reoxygenation Stimulates EDRE(s) Release from Endothelial Cells of Rabbit Aorta
- Suh, Suk-Hyo (Departments of Physiology, College of Medicine, Ewha Woman's University) ;
- Han, Jae-Jin (Departments of Thoracic Surgery, College of Medicine, Ewha Woman's University) ;
- Park, Sung-Jin (Department of Physiology & Biophysics, Seoul National University College of Medicine) ;
- Choi, Jai-Young (Department of Physiology & Biophysics, Seoul National University College of Medicine) ;
- Sim, Jae-Hoon (Department of Physiology & Biophysics, Seoul National University College of Medicine) ;
- Kim, Young-Chul (Department of Physiology & Biophysics, Seoul National University College of Medicine) ;
- Kim, Ki-Whan (Department of Physiology & Biophysics, Seoul National University College of Medicine)
- 발행 : 1999.08.21
초록
We have reported that hypoxia stimulates EDRF(s) release from endothelial cells and the release may be augmented by previous hypoxia. As a mechanism, it was hypothesized that reoxygenation can stimulate EDRF(s) release from endothelial cells and we tested the hypothesis via bioassay experiment. In the bioassay experiment, rabbit aorta with endothelium was used as EDRF donor vessel and rabbit carotid artery without endothelium as a bioassay test ring. The test ring was contracted by prostaglandin