The Korean Journal of Physiology and Pharmacology
- 제3권3호
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- Pages.351-356
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- 1999
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- 1226-4512(pISSN)
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- 2093-3827(eISSN)
Altered Calcium Current of the Vascular Smooth Muscle in Renal Hypertension
- Nam, Sang-Chae (Department of Physiology, Chonnam University Medical School) ;
- Jeong, Hye-Jeon (Department of Physiology, Chonnam University Medical School) ;
- Kim, Won-Jae (Department of Oral Biology, Chonnam University Dental School) ;
- Lee, Jong-Un (Department of Physiology, Chonnam University Medical School)
- 발행 : 1999.06.21
초록
The present study was aimed at investigating whether the calcium current in the vascular smooth muscle (VSM) cells is altered in renal hypertension. Two-kidney, one clip (2K1C) and deoxycorticosterone acetate (DOCA)-salt hypertension were made in Sprague-Dawley rats. Rats without clipping the renal artery or implanting DOCA were used as control for 2K1C and DOCA-salt hypertension, respectively. Four weeks after clipping, systolic blood pressure was significantly higher in 2K1C rats than in control
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