동의생리학회지 (Journal of Oriental Physiology)
- 제14권2호통권20호
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- Pages.43-54
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- 1999
방풍통성산(防風通聖散)이 L-NAME 유발 및 SHR 흰쥐의 고혈압에 미치는 영향
Effect of Bangpoongtongsungsan on the Hypertention induced by L-NAME injection and SHR in Rats
- Lee, Young-Hwa (Dept. of Physiology, College of Oriental Medicine, Dong-Eui University) ;
- Kim, Kyung-Chul (Dept. of Physiology, College of Oriental Medicine, Dong-Eui University) ;
- Lee, Yong-Tae (Dept. of Physiology, College of Oriental Medicine, Dong-Eui University)
- 발행 : 1999.09.01
초록
In order to get the effect of Bangpoongtongsungsan (BPS) water extract on the blood pressure of every 5 group of rats (in normal state of after 3 hours of unanesthetized) was measured and following results were obtained. 1. BPS intraperitoneal injection was not recognized as having the effect of decreasing blood pressure compared with Control on hypertension induced by L-NAME in young rats. 2. BPS oral administration was recognized as having the effect of decreasing blood pressure compared with Control on hypertension induced by L-NAME in young rats. 3. BPS oral administration was recognized as having the effect of decreasing blood pressure compared with Control on hypertension induced by L-NAME's continual injection and BPS continual oral administration in young rats. 4. BPS oral administration was recognized as having the effect of decreasing blood pressure compared with Control on hypertension induced by L-NAME's in adult rats. 5. BPS oral administration was not recognized as having the effect of decreasing blood pressure compared with Control on spontaneous hypertension rats. According to the above results. it is known that BPS extract oral administration decreased the blood pressure of hypertension induced by and more effective to the youth.