Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
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A Case of Primary Pulmonary Sarcoma with Morphologic Features of Biphasic Synovial Sarcoma

원발성 폐육종 1예 : 이상성 활막육종(Biphasic Synovial Sarcoma)

  • Song, So-Hyang (Department of Internal Medicine, Catholic University Medical College) ;
  • Lee, Kwan-Hyung (Department of Internal Medicine, Catholic University Medical College) ;
  • Oh, Jeong-Hwan (Department of Internal Medicine, Catholic University Medical College) ;
  • Moon, Hwa-Sik (Department of Internal Medicine, Catholic University Medical College) ;
  • Song, Jeong-Sup (Department of Internal Medicine, Catholic University Medical College) ;
  • Park, Sung-Hak (Department of Internal Medicine, Catholic University Medical College) ;
  • Kim, Kyoung-Mee (Department of Clinical Pathology, Catholic University Medical College) ;
  • Lee, An-Hi (Department of Clinical Pathology, Catholic University Medical College)
  • 송소향 (가톨릭대학교 의과대학 내과학교실) ;
  • 이관형 (가톨릭대학교 의과대학 내과학교실) ;
  • 오정환 (가톨릭대학교 의과대학 내과학교실) ;
  • 문화식 (가톨릭대학교 의과대학 내과학교실) ;
  • 송정섭 (가톨릭대학교 의과대학 내과학교실) ;
  • 박성학 (가톨릭대학교 의과대학 내과학교실) ;
  • 김경미 (가톨릭대학교 의과대학 임상병리학교실) ;
  • 이안희 (가톨릭대학교 의과대학 임상병리학교실)
  • Published : 1998.12.30
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Abstract

Synovial sarcoma is a malignant soft tissue neoplasm that occurs frequently in the extremities of young adults, near large joints. The lung is a common site of metastasis but an extremely unusual primary site for synovial sarcoma. We report an unusual case of primary synovial sarcoma that arose in the lung of a 59-year-old woman. The tumor had histologic and immunophenotypic features consistent with biphasic synovial sarcoma These features included of an intimate admixture of cytokeratin and epithelial membrane antigen(EMA)-positive neoplastic epithelial cells and vimentin-positive fibroblast-like spindle cells. The patient had a closed thoracomy drainage and doxycycline pleurodesis for malignant loculated effusion and showed tumor extension in the left whole lung 4 months after pleurodesis. This case is an usual addition to the small number of published reports on primary pulmonary synovial sarcoma The distintive features of this neoplasm allow it to be distinguished from a variety of primary and metastatic malignancies in the lung.

저자들은 59세 여자환자에서 조직학적으로 면역학적으로 이상성 활막육종의 형태를 가진 원발성 폐육종 1예를 경험하였기에 이를 문헌 고찰과 함께 보고하는 바이다.

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