A Case of Pulmonary Eosinophilic Granuloma in a Passive-Smoking Reproductive Female

가임기 간접흡연 여성에서 발생한 폐 호산구성 육아종 1예

  • Shin, Jae-Ho (Department of Internal Medicine, College of Medicine, Yonsei University) ;
  • Kim, Ji-Young (Department of Pathology, College of Medicine, Yonsei University) ;
  • Oh, Soo-Hwan (Department of Internal Medicine, College of Medicine, Yonsei University) ;
  • Park, Hong-Soo (Department of Internal Medicine, College of Medicine, Yonsei University) ;
  • Chung, Sang-Su (Department of Internal Medicine, College of Medicine, Yonsei University) ;
  • Na, Sang-Kyu (Department of Internal Medicine, College of Medicine, Yonsei University) ;
  • Kim, Hyung-Jung (Department of Internal Medicine, College of Medicine, Yonsei University) ;
  • Ahn, Chul-Min (Department of Internal Medicine, College of Medicine, Yonsei University) ;
  • Kim, Hae-Kyun (Department of Thoracic Surgery, College of Medicine, Yonsei University) ;
  • Kim, Sang-Jin (Department of Radiology, College of Medicine, Yonsei University) ;
  • Cho, Sang-Ho (Department of Pathology, College of Medicine, Yonsei University)
  • 신재호 (연세대학교 의과대학 내과학교실) ;
  • 김지영 (연세대학교 의과대학 병리학교실) ;
  • 오수환 (연세대학교 의과대학 내과학교실) ;
  • 박홍수 (연세대학교 의과대학 내과학교실) ;
  • 정상수 (연세대학교 의과대학 내과학교실) ;
  • 나상규 (연세대학교 의과대학 내과학교실) ;
  • 김형중 (연세대학교 의과대학 내과학교실) ;
  • 안철민 (연세대학교 의과대학 내과학교실) ;
  • 김해균 (연세대학교 의과대학 흉부외과학교실) ;
  • 김상진 (연세대학교 의과대학 방사선과학교실) ;
  • 조상호 (연세대학교 의과대학 병리학교실)
  • Published : 1998.04.30

Abstract

Pulmonary eosinophilic granuloma, a rare form of Langerhans cell histiocytosis confined to lung, has no known etiology and variable natural history. It is characterized by discrete proliferation of Langerhans cells. It is known that over 90% of the patients are cigarette smokers, and it is rarely reported in non- or passive-smoking patients, especially female. Here we describe a case of pulmonary eosinophilic granuloma in a passive-smoking, reproductive female patient presented with spontaneous pneumothorax. We identified S-100 and CDla positive histiocytes on immunohistochemical stain of the lung tissue obtained by open lung biopsy.

기흉과 미만성 간질성 폐질환의 소견을 보인 흡연력이 없는 젊은 여자 환자에서 개흉 폐생검후 면역조직화학염색을 통하여 폐 호산구성 육아종을 진단한 1예를 경험하였기에 보고하는 바이다.

Keywords