대한두경부종양학회지 (Korean Journal of Head & Neck Oncology)
- 제14권2호
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- Pages.156-163
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- 1998
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- 1229-5183(pISSN)
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- 2586-2553(eISSN)
국소재발된 두경부종양의 무고정틀 정위적 분할방사선치료
Frameless Fractionated Stereotactic Radiaton Therapy in Recurrent Head & Neck Cancers
- 김인아 (가톨릭대학교 의과대학 성모병원 방사선종양학과) ;
- 최일봉 (가톨릭대학교 의과대학 성모병원 방사선종양학과) ;
- 장지영 (가톨릭대학교 의과대학 성모병원 방사선종양학과) ;
- 강기문 (가톨릭대학교 의과대학 성모병원 방사선종양학과) ;
- 조승호 (가톨릭대학교 의과대학 성모병원 이비인후과) ;
- 김형태 (가톨릭대학교 의과대학 성모병원 이비인후과) ;
- 이경진 (가톨릭대학교 의과대학 성모병원 신경외과) ;
- 최창락 (가톨릭대학교 의과대학 성모병원 신경외과)
- Kim In-Ah (Department of Radiation Oncology, St. Mary's Hospital, College of Medicine, Catholic University of Korea) ;
- Choi Ihl-Bhong (Department of Radiation Oncology, St. Mary's Hospital, College of Medicine, Catholic University of Korea) ;
- Jang Ji-Young (Department of Radiation Oncology, St. Mary's Hospital, College of Medicine, Catholic University of Korea) ;
- Kang Ki-Mun (Department of Radiation Oncology, St. Mary's Hospital, College of Medicine, Catholic University of Korea) ;
- Jho Seung-Ho (Department of Otolaryngology, St. Mary's Hospital, College of Medicine, Catholic University of Korea) ;
- Kim Hyung-Tae (Department of Otolaryngology, St. Mary's Hospital, College of Medicine, Catholic University of Korea) ;
- Lee Kyung-Jin (Department of Neurosurgry, St. Mary's Hospital, College of Medicine, Catholic University of Korea) ;
- Choi Chang-Rak (Department of Neurosurgry, St. Mary's Hospital, College of Medicine, Catholic University of Korea)
- 발행 : 1998.11.01
초록
Background & Objectives: Frameless fractionated stereotactic radiotherapy(FFSRT) is a modification of stereotactic radiosurgery(SRS) with radiobiologic advantage of fractionation without losing mechanical accuracy of SRS. Local recurrence of head and neck cancer at or near skull base benefit from reirradiation. Main barrier to successful palliation is dose limitation secondary to normal tissue tolerance. We try to evaluate the efficacy and safety of FFSRT as a new modality of reirradaton in these challenging patients. Materials & Methods: Seven patients with recurrent head & neck cancer involving at or near skull base received FFSRT from September 1995 to November 1997. Six patients with nasopharyngeal cancer had received induction chemotherapy and curative radiation therapy. One patient with maxillary sinus cancer had received total maxillectomy and postoperative radiation therapy as a initial treatment. Follow-up ranged from 11 to 32 months with median of 24 months. Three of 7 patients received hyperfractionated radiation therapy(1.1-1.2Gy/fraction, bid, total 19.8-24Gy) just before FFSRT. All patients received FFSRT(3-5Gy/fraction, total 15-30Gy/5-10fractions). Chemotherapy(cis-platin