경골 이식의 골결손부 골재생에 대한 실험적 연구

AN EXPERIMENTAL STUDY ON THE BONE REGENERATION OF TIBIAL BONE DEFECT

  • 김수관 (조선대학교 치과대학 구강악안면외과학교실, 구강생물학연구소) ;
  • 여환호 (조선대학교 치과대학 구강악안면외과학교실, 구강생물학연구소) ;
  • 김수민 (조선대학교 치과대학 구강악안면외과학교실, 구강생물학연구소)
  • Kim, Su-Gwan (Dept. of Oral & Maxillofacial Surgery, Oral Biology Research Institute, College of Dentistry, Chosun University) ;
  • Yeo, Hwan-Ho (Dept. of Oral & Maxillofacial Surgery, Oral Biology Research Institute, College of Dentistry, Chosun University) ;
  • Kim, Soo-Min (Dept. of Oral & Maxillofacial Surgery, Oral Biology Research Institute, College of Dentistry, Chosun University)
  • 투고 : 1998.09.11
  • 심사 : 1998.10.02
  • 발행 : 1998.12.31

초록

Recently, the clinical applications of the autogenous cancellous bone from the proximal tibial metaphysis show satisfactory results in the repair of maxillofacial bony defect or deformity. The proximal tibia has the potential to yield viable cancellous bone with a minimum of morbidity. The purpose of this study was to investigate the regeneration of a full thickness proximal tibial bone defect with covering or uncovering of cortical bone. The follow-up periods were 4, 8, and 12 weeks. Bone defect of right side was uncovered and left side was covered with cortical bone. In the experimental group (uncovered cortical bone) at 12 weeks, the inside of defect was filled to normal marrow tissue. The cortical bone defect was united of inner, outer callus at 4, 8 weeks in both study group. At 12 weeks, the cortical bone defect was remodeled and invaded by osteoclast (giant cell) in experimental group. In the experimental specimen at 12 weeks, the regenerating tissue of bone defect was not differ from the control group.

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