Restorative Dentistry and Endodontics

The Korean Academy of Conservative Dentistry (대한치과보존학회)
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THE EFFECT OF POLYPHOSPHATE ON THE GROWTH OF PORPHYROMONAS ENDODONTALIS

Polyphosphate가 Porphyromonas endodontalis의 성장에 미치는 영향에 관한 연구

  • Choi, Sung-Baik (Department of Conservative Dentistry, College of Dentistry, Kyung-Hee University) ;
  • Choi, Ho-Young (Department of Conservative Dentistry, College of Dentistry, Kyung-Hee University) ;
  • Min, Byung-Soon (Department of Conservative Dentistry, College of Dentistry, Kyung-Hee University) ;
  • Park, Sang-Jin (Department of Conservative Dentistry, College of Dentistry, Kyung-Hee University) ;
  • Lee, Jin-Yong (Department of Conservative Dentistry, College of Dentistry, Kyung-Hee University) ;
  • Choi, Ki-Woon (Department of Conservative Dentistry, College of Dentistry, Kyung-Hee University)
  • 최성백 (경북대학교 치과대학 보존학교실) ;
  • 최호영 (경북대학교 치과대학 보존학교실) ;
  • 민병순 (경북대학교 치과대학 보존학교실) ;
  • 박상진 (경북대학교 치과대학 보존학교실) ;
  • 이진용 (경북대학교 치과대학 보존학교실) ;
  • 최기운 (경북대학교 치과대학 보존학교실)
  • Published : 1998.04.07
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Abstract

Polyphosphate has been used to prevent decomposition of foods and has been shown to have inhibitory effect on the growth of gram positive bacteria. The purpose of this study was to evaluate the effect of polyphosphate on the growth of Porphyromonas endodontalis, a gram negative endodontopathic bacterium. Porphyromonas endodontalis ATCC 35406 was grown in the presence of polyphosphates with different chain lengths. Inhibitory effect of each polyphosphate which was added at the beginning or during the culture, was determined by measuring the optical density of the bacterial cell at 540nm and by viable cell count. The results from this study were as follows : 1. Polyphosphates were shown the growth inhibition of the Porphyromonas endodontalis. 2. The minimal inhibitory concentration(MIC) of polyphosphate was observed to be 0.04%. 3. Polyphosphates with chain lengths of 25 and 75 demonstrated the greatest inhibitory effect on the growth of Porphyromonas endodontalis. 4. Polyphosphates are bactericidal to Porphyromonas endodontalis, demonstrating the growth inhibition of the bacterium. The overall results suggest that use of polyphosphate may affect the growth of Porphyromonas endodontalis. Further studies will be needed to confirm the effect of, polyphosphate.

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