The Journal of Korean Academy of Prosthodontics (대한치과보철학회지)
- Volume 36 Issue 6
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- Pages.816-831
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- 1998
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- 0301-2875(pISSN)
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- 2005-3789(eISSN)
AN EXPERIMENTAL STUDY OF PLATELET-DERIVED GROWTH FACTOR ABOUT BONE FORMATION IN DENTAL IMPLANT
혈소판 유래 성장인자가 임플란트 주위 골형성에 미치는 효과에 대한 실험적 연구
- Ryu, Jae-Jun (Major in Dentistry, Department. of Medical Science, Korea University) ;
- Kwon, Jong-Jin (Major in Dentistry, Department. of Medical Science, Korea University) ;
- Kim, Han-Kyum (Major in Dentistry, Department. of Medical Science, Korea University)
- Published : 1998.12.01
Abstract
Bony fixation of implants during the early phase of healing is important in order to get secondary stability of the implant assuring the success of the treatment. Because the successful placement of the implant is limited by the quality and quantity of bone, other agents which stimulate bone formation in the peri-implant spaces has been illustrated. Platelet-derived growth factor (PDGF) has been shown to regulate DNA and protein synthesis in bone cells in vitro and to interact synergistically to enhance soft tissue wound healing in vivo. The purpose of this study was to evaluate bone promotion around implants which were augmented with sagittal split osteotomy or autogenous veneer bone graft using the platelet derived growth factor(PDGF). After placement of newly designed twenty four screw-type implants, which were 12mm in length and 4mm in diameter in 6 dogs.
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