Journal of Preventive Medicine and Public Health

The Korean Society for Preventive Medicine (대한예방의학회)
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The Association between Job Characteristics, Psychosocial Distress and Homocysteine

직업적 특성, 사회심리적 스트레스 및 호모시스테인의 관련성

  • Cha, Bong-Suk (Department of Preventive Medicine and Institute of Occupational Medicine, Wonju College of Medicine, Yonsei University) ;
  • Koh, Sang-Baek (Department of Preventive Medicine and Institute of Occupational Medicine, Wonju College of Medicine, Yonsei University) ;
  • Chang, Sei-Jin (Department of Preventive Medicine and Institute of Occupational Medicine, Wonju College of Medicine, Yonsei University)
  • 차봉석 (연세대학교 원주의과대학 예방의학교실 및 직업의학연구소) ;
  • 고상백 (연세대학교 원주의과대학 예방의학교실 및 직업의학연구소) ;
  • 장세진 (연세대학교 원주의과대학 예방의학교실 및 직업의학연구소)
  • Published : 1998.12.01
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Abstract

This study was carried out to assess the relationship between jobstrain, psychosocial distress and homocysteine. The study design was cross-sectional, and included 152 industrial workers in middle sized city. A self-adminstered questionnaire measured general characteristic, job strain and psychosocial distress. Blood was drawn into EDTA tube, and total plasma homocysteine was measured by HPLC. Homocysteine in the high job demand group was sagnificantly higher than that in the low job demand. Cholesterol in the high job control group was significantly higher than that in the low job control. Homocysteine was significantly higher in the high job strain group than that in the other group. Folate and vitamin B12 showed a significantly negative correlation with homocysteine. Multiple regression analysis was used to determine whether the psychosocial distress and other variable contributed to explaining the homocysteine. Stress correlates with the homocysteine.

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