한국응용과학기술학회지 (Journal of the Korean Applied Science and Technology)
- 제15권2호
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- Pages.49-57
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- 1998
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- 1225-9098(pISSN)
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- 2288-1069(eISSN)
DOI QR Code
Deamination과 Nitration반응을 이용한 아닐린과 Isoquinoline 유도체의 합성
Synthesis of Aniline and Isoquinoline derivatives using Deamination and Nitration
- Yoon, Cheol-Hun (Dept. of chemical engineering, Myung Ji University) ;
- Lee, Ki-Chang (Dept. of chemical engineering, Myung Ji University)
- 발행 : 1998.06.30
초록
This study is to develop a new synthetic method for the nitroarenes via non-electrophilic substitution. Direct nitration at the C-1 position of isoquinoline has never been reported and substitution in isoquinoline under the normal nitration condition occurs at C-5 and C-8. We have demonstrated a facile one-step sythetic method for the nitration of isoquinolines at the C-1 position, which involves the electrophilic attack of a
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