The Korean Journal of Cytopathology (대한세포병리학회지)
- Volume 9 Issue 1
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- Pages.63-68
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- 1998
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- 1017-0391(pISSN)
Morphometric Study on Fine Needle Aspirates from Follicular Adenoma and Follicular Carcinoma of the Thyroid
세침흡인된 갑상선의 여포상 선종과 여포상 암종의 형태계측학적 연구
- Chu, Young-Chae (Department of Anatomical Pathology, Inha Hospital) ;
- Cha, Hee-Jung (Department of Anatomical Pathology, Inha Hospital) ;
- Min, Soo-Kee (Department of Anatomical Pathology, Inha Hospital) ;
- Kim, Joon-Mee (Department of Anatomical Pathology, Inha Hospital) ;
- Hwang, Tae-Sook (Dept. of Pathology, Inha University)
- 주영채 (인하대학교 인하병원 해부병리과) ;
- 차희정 (인하대학교 인하병원 해부병리과) ;
- 민수기 (인하대학교 인하병원 해부병리과) ;
- 김준미 (인하대학교 인하병원 해부병리과) ;
- 황태숙 (인하대학교 인하병원 병리학교실)
- Published : 1998.06.30
Abstract
Fine needle aspiration cytology of "cold" nodules of the thyroid has proved to be of great value in their preoperative diagnosis. Most types of thyroid tumors are readily recognizable from characteristic cellular patterns in the smears of needle aspirates. But follicular neoplasms present some problems because the cytomorphology of the adenomas frequently is same as in carcinoma. For differentiation of benign from malignant follicular neoplasms of the thyroid we tested the usefulness of two objective parameters - nuclear area and perimeter - by morphometry. This study was made on fine needle aspirates from 30 cases with cytologic diagnosis of follicular neoplasm of thyroid. The histologic classification was follicular adenoma in 22 cases and follicular carcinoma in 8 cases. As a reference group we used seven caes with nodular hyperplasia. The smears of aspirates were stained by Papanicolaou method. On each slide 200 randomly selected cells with intact nuclei were measured. The mean value of nuclear area are