대한한방종양학회지 (THE JOURNAL OF KOREAN ORIENTAL ONCOLOGY)
- 제4권1호
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- Pages.89-110
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- 1998
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- 1229-2621(pISSN)
육미지황탕(六味地黃湯)이 생리활성지표(生理活性指標)와 임파구세포수(淋巴球細胞數)에 미치는 영향(影響)
Correlative Effects of Yookmijihwangtang(六味地黃湯) on the T helper cell count, Blood cAMP, Testosterone and Cortisol
- Kim, Young-Kuen (Dept. of Digestive Internal Medicine, the College of Oriental Medicine, Kyung Hee Univ.) ;
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Ryu, Bong-Ha
(Dept. of Digestive Internal Medicine, the College of Oriental Medicine, Kyung Hee Univ.) ;
- Park, Dong-Won (Dept. of Digestive Internal Medicine, the College of Oriental Medicine, Kyung Hee Univ.) ;
- Ryu, Ki-Won (Dept. of Digestive Internal Medicine, the College of Oriental Medicine, Kyung Hee Univ.)
- 발행 : 1998.12.21
초록
Yookmijihwangtang has been widely used oriental herb prescriptions, which is healing some discuss that come from insufficiency of innate essence and deficiency of kidney Ki. The meaning of healing discusses tonification of insufficient innate essence and insufficient kidney Ki can be regarded as reinforcement of wholely power of keeping homeostasis, that is correlated with immuno-responsibility which protects subject from outer antigen to keep normal vital condition. This study was aimed to investigate correlative effects of Yookmijihwangtang water abstract on the RBC, WBC, blood CD4+ T helper cell count, blood testosterone, blood cAMP and blood cortisol. 40 Sprague-Dawley male rats were divided into 5 groups(Normal, Control, Sample I, Sample II, Sample III), 6 animals in every group. Normal group was not treated anything, control group was administrated normal saline in the same dosage of Sample I. 3 Sample groups were received some of Yookmijihwangtang water abstract at one time per 24 hours during 5 days in different dosage. Sample I(1/310pack/ml), Sample II(1/62pack/ml), Sample III(1/2.4pack/ml). After finishing treatment, all experimental subjects were killed for blood sample on RBC, WBC, blood CD4+ T helper cell count, spleen CD4+ T helper cell count, axillary lymph node CD4+ T helper cell count. blood cAMP, blood testosterone and blood cortisol. The results were as follows; RBC and WBC were increased in all sample groups. Blood CD4+ T helper cell count(CD4+ T cell count in the blood/whole lymphocyte count in the blood