골다공증의 표식자로서 방사선학적 fracrtal dimension의 유용성에 관한 연구

Fractal dimension from radiographs of bone as indicators of possible osteoporosis

The purpose of this study was to investigate whether a radiographic estimate of osseous fractal dimension is useful in the characterization of structural changes in bone. Ten specimens of bone were progressively decalcified in fresh 50 ml solutions of 0.1 N hydrochloric acid solution at cummulative timed periods of 5, 10, 20, 30, 60 and 90 minutes, and radiographed from 0 degree projection angle controlled by intraoral parelleling device. The test set of 70 radiographs was digitized and digitally filtered to reduce film -grain noise. I performed one-dimensional variance and fractal analysis of bony profiles or scan lines. Correlation analysis quantified the relationship between variance and fractal dimension. The obtained results were as follow. 1. After the first stage of decalcification variance and fractal dimension of scan line pixel intensities generally decreased with a range of 57.94 to 12.64 and 1.59 to 1.36. 2. Correlation coefficient(r) relating variances to fractal dimensions was consistantly excellent(range r=0.90 to 0.98). 3. Variance and fractal dimension were much alike in ability to discriminate, at leat on a group basis, between control and decalcified specimens.