YAKHAK HOEJI (약학회지)
- Volume 42 Issue 6
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- Pages.589-597
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- 1998
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- 0377-9556(pISSN)
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- 2383-9457(eISSN)
Effects of Mori Folium Ethanol Soluble Fraction on mRNA Expression of glucose transporters, acetyl-CoA carboxylase and leptin
상엽 에탄올가용분획의 글루코스전달체, acetyl-CoA 카복시라제 및 렙틴 mRNA 발현에 미치는 영향
- Ryu, Jeong-Wha (College of Pharmacy, Kyung Hee University) ;
- Yook, Chang-Soo (College of Pharmacy, Kyung Hee University) ;
- Chung, Sung-Hyun (College of Pharmacy, Kyung Hee University)
- Published : 1998.12.01
Abstract
Effects of Mori Folium Ethanol Soluble Fraction (MFESF) on mRNA expression of glucose transporters, acetyl-CoA carboxylase (ACC) and leptin were examined in db/db mice. 500 and 1000mg/kg dose for MFESF (designated by SY 500 and SY 1000, respectively) and 5mg/kg dose for acarbose were administered for 6 weeks. Quantitations of glucose transporters (GLUT-2 and GLUT-4), ACC and leptin mRNA were performed by RT-PCR and in vitro transcription with co-amplification of rat
Keywords
- Mori Folium;
- db/db mouse;
- GLUT-2;
- GLUT-4;
- acetyl-CoA carboxylase;
- leptin;
- RT-PCR;
- in vitro transcription