Toxicological Research
- Volume 14 Issue 3
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- Pages.333-339
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- 1998
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- 1976-8257(pISSN)
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- 2234-2753(eISSN)
Effects of Sambutoxin on the Rabbit Platelet Aggregation
Sambutoxin이 토끼의 혈소판 응집에 미치는 영향
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Hong, Choong-Man
(Department of Pathology, National Institute of Toxicology Research) ;
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Cho, Myung-Haeng
(College of Veterinary Medicine, Seoul National University)
- Published : 1998.09.01
Abstract
Sambutoxin, a newly purified mycotoxin in Koea, caused hemorrhage in the stomach and intestine of rats. To elucidate the mechanism of hemorrhage, effects of sambutoxin on rabbit platelet aggregation were investigated. First of all, the effects of sambutoxin on the platelet aggregation response and ATP release from platelet by various appregating factors were investigated. And then the role of