Clinical and Experimental Reproductive Medicine
- 제25권2호
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- Pages.233-237
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- 1998
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- 2233-8233(pISSN)
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- 2233-8241(eISSN)
원형정자세포의 주입에 의한 임신과 분만 1례
Pregnancy and Delivery by Round Spermatid Injection into Oocytes in Human
- 이상민 (하나병원 불임연구실) ;
- 정지영 (하나병원 불임연구실) ;
- 한용태 (하나병원 불임연구실) ;
- 박해택 (하나병원 불임연구실) ;
-
박흠대
(대구대학교 공과대학)
;
- 정길생 (건국대학교 축산대학) ;
- 이기영 (하나병원 불임연구실)
- Lee, S.M. (Infertility Research Center, Hana Women's Hospital) ;
- Jung, J.Y. (Infertility Research Center, Hana Women's Hospital) ;
- Han, Y.T. (Infertility Research Center, Hana Women's Hospital) ;
- Park, H.T. (Infertility Research Center, Hana Women's Hospital) ;
-
Park, H.D.
(College of Engineering, Daegu University)
;
- Chung, K.S. (College of Animal Husbandry, Kon-Kuk University) ;
- Lee, K.Y. (Infertility Research Center, Hana Women's Hospital)
- 발행 : 1998.06.30
초록
We demonstrated that the normal pregnancy and delivery by round spermatid injection (ROSI) into oocytes was achieved from nonobstructive azoospermia patient. In this case, the normal fertilization rate was 50%. All of the two pronuclear stage embryos cleaved and were transferred to the patient's uterus. A singleton pregnancy was achieved and resulted in the birth of normal female infant. This resuJt show that intracytoplasraic injection of round spermatid seems to be new treatment of nonobstmctive azoospermia male infertility. Further research is needed to evaluate the required culture conditions to induce progression of the round spermatid into a more elongated stage.