KOREAN JOURNAL OF CROP SCIENCE (한국작물학회지)
- Volume 43 Issue 3
- /
- Pages.168-171
- /
- 1998
- /
- 0252-9777(pISSN)
- /
- 2287-8432(eISSN)
Antitumor Activity of Crude Sesaminol in Sesame Seed
- Ryu, Su-Noh (National Crop Experiment Station, Rural Development Administration) ;
- Lee, Bong-Ho (National Crop Experiment Station, Rural Development Administration)
- Published : 1998.09.01
Abstract
Sesaminol in sesame seed was postulated to have antitumor activity. The present study was performed to characterize the role of crude sesaminol extracted from sesame seed (Sesame Crude Sesaminol; SCS) on inhibiting the in vitro growth of human leukemia HL-60 cells. SCS inhibited the growth of human leukemia HL 60 cells in culture and macromolecular synthesis in a dose and time dependent manner. The cytostatic range of SCS concentration was found to be 60 to 100