한국환경성돌연변이발암원학회지 (Environmental Mutagens and Carcinogens)
- 제18권2호
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- Pages.83-88
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- 1998
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- 1225-6307(pISSN)
온도 기울기(temperature gradient) 젤에서 Heteroduplex Analysis 기법을 이용한 돌연변이 DNA의 검출
Detection of Mutated DNA Fragment by the Heteroduplex Analysis at the Temperature Gradient Gel
초록
To detect the mutation in a given sequence, there are variety of methods developed by use of the gel electrophoresis. One of the methods, TGGE (Temperature Gradient Gel Electrophoresis), is a popular technique because it can detect mutations in DNA fragment with ease and at low cost. This study used 200 bp BamHI-digested DNA fragment containing the human