성장기 흰쥐에서 붕소의 보충이 체내 칼슘 및 골격 대사에 미치는 영향

Effect of Boron Supplementation on Ca and Bone Metabolism in Rats during Growth

  • 정혜경 (호서대학교 자연과학대학 식품영양학과) ;
  • 이현숙 (이화여자대학교 가정과학대학 식품영양학과) ;
  • 김종연 (호서대학교 자연과학대학 식품영양학과) ;
  • 김종여 (단국대학교 치과대학 구강조직학과)
  • 발행 : 1998.07.01

초록

It has been reported that boron may be beneficial for optimal calcium metabolism and, thus, optimal bone metabolism. Therefore, we designed a study to determine the effect of boron supplementation on Ca and bone metabolism in rats. The rats of 80-l40g body weight were given a control(0ug), 5$\mu\textrm{g}$, 10$\mu\textrm{g}$, 20$\mu\textrm{g}$, 40$\mu\textrm{g}$, or 80$\mu\textrm{g}$ boron supplement per Is diet for 4-weeks. The results are summarized as follows. There were no differences in total food intake and weight gain among the experimental groups. fecal Ca excretion, urinary Ca excretion, apparent Ca absorption, Ca retention, serum alkaline phosphatase activity, and urinary hydroxyproline were not affected by boron supplementation. There was no difference in serum creatinine. Whereas, urinary creatinine excretion was increased with increasing boron supplementation, and conse-quently creatinine clearance was increased with boron supplementation. No differences were found in length, weight, density, Ca content of femur and scapular. The findings suggest that boron supplementation was not effective in Ca and bone metabolism in growing rats fed normal Ca diet. (Korean J Nutrition 31(6) : 1039-1048, 1998)

키워드

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