Journal of the Korean Magnetic Resonance Society (한국자기공명학회논문지)
- Volume 2 Issue 2
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- Pages.152-157
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- 1998
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- 1226-6531(pISSN)
RNA-Protein Interactions and Protein-Protein Interactions during Regulation of Eukaryotic Gene Expression
- Varani, Luca (MRC Laboratory of Molecular Biology) ;
- Ramos, Andres (MRC Laboratory of Molecular Biology) ;
- Cole, Pual T. (MRC Laboratory of Molecular Biology) ;
- Neuhaus, David (MRC Laboratory of Molecular Biology) ;
- Varani, Gabriele (MRC Laboratory of Molecular Biology)
- Published : 1998.12.01
Abstract
The diversity of RNA functions ranges from storage and propagation of genetic information to enzymatic activity during RNA processing and protein synthesis. This diversity of functions requires an equally diverse arrays of structures, and, very often, the formation of functional RNA-protein complexes. Recognition of specific RNA signals by RNA-binding proteins is central to all aspects of post-transcriptional regulation of gene expression. We will describe how NMR is being used to understand at the atomic level how these important biological processes occur.
Keywords