The Effect of Fentazine-induced Sedation in Farmed Elk (Cervus canadensis)

사육 엘크의 Fentazine 진정효과

  • Published : 1998.06.01

Abstract

This study was performed to assess clinical signs, sedative effect and clinicschemical profile of a mixture of fentanyl-azapemne-xylazine(Fentazine$^{(R)}$) in formed elk Twelve male elk(Cervus canadensis) were immobilized with Fentazine, and blood samples were taken of femoral venous blood. Samples were analyzed in the conditions of 10- and 30-minute after administration of the drug. Heart rates, respiratory rates, and body temperatures were in normal ranges during Fentazine anesthesia. After iqiection of Fentazine, most of elk were recumbency and did not respond to needle prick In young adult(3.5.4.5 years old) elk a high dose(>3.0 ml/head) of Fentazine does not result in more sedation, but it does prolong the duration of sedative effect. Fentazine induced sufficient analgesia far velvet antler removal and hoof trimming in elk Salivation, urination, intermittent apnea and mild bloat were observed in elk Globulin, alanine aminotransferase, aspartate aminotransferase, blood urea nitrogen, calcium, magnesium and phosphorus values were in normal ranges for at least 30 minutes after Fentazine administration. Total protein, albumins cortisol and prothrombin values were slightly increased during sedation(p<0.05). It was concluded that Fentazine is effective analgesic drug being useful for velvet antler removal and hoof trimming.

Keywords

References

  1. Anesthesiology v.51 Fentanyl concentration in brain and serum during respiratory acid-base changes in the dog Ainslie SG;Eisele JH;Corkill G
  2. Anesthesiology v.61 Fentanyls analgesic, respiratory, and cardiovascular actions in relation to dose and plasma concentration in unanesthetized dogs Arndt JO;Mikat M;Parasher C
  3. Anesthesiology v.63 Acute tolerance to fentanyl during anesthesia in dogs Askitopoulu H;Whitwam JG;Al-Khudhari D;Chakrabarti M;Bower S;Hull CJ
  4. Anethesiology v.66 Is fentanyl an anesthetic in the dog? Bailey PL;Port JD;McJames S;Reinersman L;Stanley TH
  5. Vet Rec v.114 Duration of analgesia in sheep under xylarzine/ketamine anaethesia Byagagaire SD;Mbiuki SM
  6. Vet Res v.92 An analysis of the results of field experiments in pigs in the U.K. and Eire with the combination-anesthetic azaperone and metomidate Callear JFF;Van Gestel JFE
  7. Am J Vet Res v.40 Hemodynamic effects of xylazine in the calf Campbell KB;Klavano PA;Richardson P;Alexander JE
  8. JAVMA v.176 Xylazine Davis LE
  9. Can J Vet Res v.50 Cardiopulmonary effects of xylazine and yohimbine in laterally recumbent sheep Doherty TJ;Pascoe PJ;McDonell WN;Montrith G
  10. Am J Vet Res v.40 Xylazine-induced heperglycemia in beef cattle Erchner RD;Prior RL;Kvansnicka WG
  11. Vet Med Rev Experimental and clinical studies of the effect of Rompun in cattle Goranov S;Nejschev O;Koitschev K
  12. J Vet Pharmacol Therap v.11 Xylazine-a review of its pharmacology and use in veterinary medicine Greene SA;Thuemon JC
  13. Res Vet Sci v.53 no.3 Stress factors influencing plasma cortisol levels and adrenal weights in Chinese water deer(Hydropotes inermis) Hasting BE;Abbott DE;George LM;Stadler SG
  14. Endocrinology v.109 Xylazine-induced hyperglycemia in cattle; A possible involvement of α₂-adrenergic receptors regulating insulin release Hsu WH;Hummel SK
  15. JAVMA v.190 Effects of tolazoline and yohimbine on xylazine-induced central nerve system depression, bradycardia, and tachypnea in sheep Hsu WH;Schaffer DD;Hanson CE
  16. JAVMA v.185 Effects of yohimbine on xylazine-induced immobolization in white-tailed deer Hsu WH;Shulaw WP
  17. JAVMA v.183 Immobilization of mule deer with ketamine and xylazine, and reversal of immobilization with yohimbine Jessup DA;Clark WE;Gullet PA;Jones KR
  18. Am J Vet Res v.54 Antionocieceptive effects of combine low doses of neuloleptic drugs and fentanyl in sheep Kyles AE;Waterman AE;Vetmed ALB
  19. Br J Phamarc v.56 Effect of azaperone on cardiovascular and respiratory functions in the horse Less P;Serrano L
  20. Am J Vet Res v.36 Evaluation of xylazine as a sedative and preanesthetic agent in horses McCashin FB;Gabel AA
  21. J Anat v.158 Changes in blood content and histology during growth of antlers in red deer(Cervus elaphus) and their relationshiop to plasma testosterone levels Muir PD;Sykes AR;Barrell GK
  22. JAVMA v.167 Xylazine as an immobilizing agent for captive white-tailed deer Roughton RD
  23. Vet Med Rev The clinical application of combined Rompun and My 301 buffaloes Samy MT;Tantawy M
  24. Vet Med Rev Studies on the effect of Rompun in sheep Shokry M;Morad HM;Khalil IA
  25. The bovine practitioner v.16 Sedation and general anesthesia in ruminants Trim CM
  26. New Zealand Veterinary Journal v.44 Xylazine and a xylazine/fentanyl/azaperone combination in farmed deer.Ⅰ. Dose rate comparison Wilson PR;Beimans J;Staffoard KJ;Veltman CJ;Spoorenberg J
  27. New Zealand Veterinary Journal v.44 Xylazine and a xylazine/fentanyl/azaperone combination in farmed deer.Ⅱ. Velvet antler removal and reversal combinations Wilson PR;Beimans J;Staffoard KJ;Veltman CJ;Spoorenberg J