한국임상수의학회지 (Journal of Veterinary Clinics)

  • 제15권1호
  • /
  • Pages.36-40
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  • 1998
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  • 1598-298X(pISSN)
  • /
  • 2384-0749(eISSN)
한국임상수의학회 (The Korean Society of Veterinary Clinics)
권호 표지

Levamisole이 양식뱀장어의 면역조절작용 및 항균효과에 미치는 영향

In vivo, Immunomodulatory and Antibacterial Reaction of Levamisole in Cultured Eel, Anguilla japonica

  • 최민순 (군산대학교 해양과학대학 수족병리학과) ;
  • 박관하 (군산대학교 해양과학대학 수족병리학과) ;
  • 조정곤 (전북대학교 수의과대학 수의학과)
  • 발행 : 1998.03.01
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초록

This experiment was carried out in order to evaluate the immunomodulatory activity of levamisole (LMS) in 5. fgrjn challenged eels with different treatment regimens: 7-day LMS treatment before the challenge, 7-day LMS treatment started simultaneously with the challenge, 14-day treatment before and after the challenge. The antibacterial effect was activated in all treated groups, with the best being obtained in the simultaneously treated group. LMS stimulated the defense mechanisms of the eel as demonstrated by increase in the level of total protein, albumin, trypsin inhibitor capacity, lysozyme activity, antibody titers antibacterial activity and survival rate. These results suggest that antibacterial effects of LMS was achieved by not only non-specific immune response but also specific one in eel.

키워드

참고문헌

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