Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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In vivo, Immunomodulatory and Antibacterial Reaction of Levamisole in Cultured Eel, Anguilla japonica

Levamisole이 양식뱀장어의 면역조절작용 및 항균효과에 미치는 영향

  • 최민순 (군산대학교 해양과학대학 수족병리학과) ;
  • 박관하 (군산대학교 해양과학대학 수족병리학과) ;
  • 조정곤 (전북대학교 수의과대학 수의학과)
  • Published : 1998.03.01
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Abstract

This experiment was carried out in order to evaluate the immunomodulatory activity of levamisole (LMS) in 5. fgrjn challenged eels with different treatment regimens: 7-day LMS treatment before the challenge, 7-day LMS treatment started simultaneously with the challenge, 14-day treatment before and after the challenge. The antibacterial effect was activated in all treated groups, with the best being obtained in the simultaneously treated group. LMS stimulated the defense mechanisms of the eel as demonstrated by increase in the level of total protein, albumin, trypsin inhibitor capacity, lysozyme activity, antibody titers antibacterial activity and survival rate. These results suggest that antibacterial effects of LMS was achieved by not only non-specific immune response but also specific one in eel.

Keywords

References

  1. Virus of lower vertebrates Immunostimulation by levamisole in rainbow trout(Salmo gairdneri) in vivo Anderson DP;Swicki AK;Dixon OW;Lizzio EF
  2. Fish Pathol v.34 no.3 Chemotheraphy against infection with multiple drug resistant strains of E. tarda in cultured eel Aoki TT;Sakaguchi T;Kitao T
  3. Fish Pathol v.18 no.2 Exotoxic substances produced by Edwardsiella tarda. Arshad UM;Arai T
  4. Nippon Susian Gakkaishi v.59 no.2 Activation of mononuclear phagocyte function of levamisole immersion in crap Baba T;Watase Y;Yoshinaga Y
  5. Clin Chem v.22 Alkaline phosphatase. Ⅰ. Kinetics and inhibition by levamisole of purified isoenzymes from humans Belle VH
  6. Biochemistry and physiology of neutrophil Edward SW
  7. Technique in fish immunology Serum antiproteases in fish. Ellis AE
  8. Dis Aaqua Org v.13 Efficacy of some antihelminthics against the swimblader nematode Anguillicola crassus of eel Anguilla anguilla under salt-water conditions Geets A;Liewes;Ollevier F
  9. J Fish Dis v.12 Lysozyme from rainbow trout, Salmo gairdneri Richardson, as an antibacterial agent against fish pathogens Grinde B
  10. J Fish Biolo v.33 Observations on the granulocyte peroxidase of teleosts: a phylogenetic perspective Hine PM;Wain JM
  11. Fish pathol v.30 no.4 Respiratory burst of Japaness eel neutrophils Idia T;Wakabayashi
  12. Fish Pathol v.25 no.2 The immunomodulatory effects of levamisole on rainbow trout, Oncorhynvhus mykiss Kajita Y;Sakai M;Astuta S;Kobayashi M
  13. Dev Comp Immunol v.9 Immunity of A in coho salmon (Oncorhynchus kisutsh) induced by modified freund's adjuvant: Its non-specific nature and the probable role of macrophages in the phenomenon Oliver G;Evelyn TPT;Lallier R
  14. J Immunol Method v.82 A simple method for the solubilization of reduced NBT, and its use as a colorimetric assay for activation of human macrophages by gamma interferon RookGAw;Steele J;Umar S;Dockrel, HM
  15. J Reticuloendothelial Society v.21 no.3 Levamisole in the modulation of the immune response: The current experimental and clinical state Symoens J;Rosenthal M
  16. Fish Pathol v.19 no.1 Immune response of eel to E. tarda lipoplysaccharide Salitai F;Kawai K;Kusuda R
  17. Fish Pathol v.20;2 no.3 Chemical composition of lipopolysaccharide from E. tarda Salitai F;Kusuda R
  18. Dev Comp immunol v.13 Immunostimulating influence of levamisole on nonspecific immunity in carp (Cyprinus carpio) Siwicki AK
  19. Dev Comp Immunol v.14 In vitro immunostimulation of rainbow trout (Oncorhynchus mykiss) spleen cells with levamisole Siwicki AD;Anderson DP;Dixon OW
  20. Vet Immunol Immunopathol v.41 Dietary in take of immnunostimulants by rainbow trout affects non-specific immunity and protein against funculosis Swicki AK;Anderson DP;Rumsey GL
  21. 한국어병학회지 v.1 no.1 양식어류에 있어서 세균성질병의 검색 및 예방 전세규
  22. 한국어병학회지 v.9 no.2 뱀장어 병어로부터 분리한 E. tarda의 약제내성 최민순;최상훈;박관하;장선일;윤창용;조정곤;송희종
  23. 한국어병학회지 v.9 no.2 양만정에서 분리한 E. tarda균에 대한 new quinolone계 약물의 항균작용 최민순;김경호;서영호;최상훈;박관하
  24. 한국어병학회지 v.10 no.1 나일 틸라피아에 대한 질병 예방제 및 면역보조제로서의 PS-K효과 분석 박경현;하제이;허민도;허성희;정현도
  25. 한국어병학회지 v.2 no.2 뱀장어의 면역반응에 대한 연구. E. tarda에 대한 혈청학적 연구 박수일