Morphometrical Analysis of Developing Renal Tubular and Glomerular Cells in Rabbit

토끼의 발생기 뇨세관과 사구체 세포들의 형태계측학적인 분석

  • 정호중 (인제대학교 의과대학 해부학 교실) ;
  • 양영철 (인제대학교 의과대학 해부학 교실) ;
  • 배기원 (고신대학교 의과대학 재활의학 교실)
  • Published : 1998.08.01

Abstract

Using morphometric technique, the present study was made of the kidney of rabbit embryo in the 13 days of the gestation. Their section areas of the renal tubules and the glomerular cells were compared with the those of adult rabbit, 1. In the developing renal tubule, the tubular section areas were larger than that of the adult, but the nuclear section areas of tubular calls were smaller than the adult. The microvilli of their cell surface were poorly developed, and their cytoplasm contained well developed mitochondria with euchromatic nucleus. 2. In the developing glomeruli. the nuclear section area of the cells of the parietal layer, the podocytes, and the endothelial cells were similar size, but their nuclei were larger than those of the adult. The cytopalsm of the podocytes contained well-developed rough endoplasmic reticulum, Golgi apparatus, and round mitochondria.

태생 13일된 토끼의 발생기 신장에서 뇨세관과 사구체 세포들의 크기와 형태를 관찰하여 성숙한 토끼의 신장과 형태계측학적으로 비교한 결과 다음과 같은 결과를 얻었다. 1. 태생 13일의 발생기 뇨세관 단면적은 성숙한 토끼의 근위세관 단면적보다 훨씬 넓고 평균직격이 길었으며 내강이 거의 없었다. 뇨세관 상피세포의 솔모양 가장자리는 발달되지 않았고 핵 위쪽에 둥근 사립체가 발달되었으며 기저막부분에는 사립체가 적었다. 2. 발생기 사구체내에는 벽측세포, 족세포, 내피세포들로 구별되었으며 성숙한 토끼보다 내피세포와 벽측세포의 세포핵 단멱적이 훨씬 컸고 성숙한 토끼의 사구체에서는 족세포가 가장 컸으나 발생기에는 내피세포의 크기가 가장 컸다.

Keywords

References

  1. Cancer v.69 The use of nuclear morphometry to predict to response to therapy Gearhart, J. P.;Partin, A. W.;Leventhal, B.;Beckwith, J. B.;Epstein, J. I.
  2. Pediatric Urolog. v.45 no.1 Nuclear morphometric analysis of metastasis in Wilms' tumor after multimodal therapy : comparison with primary tumor Gearhart, J. P.;Willmann, J. R. Q.;Beckwith, J. B.
  3. J. Urolog. v.154 Nuclear morphometry in differential diagnosis of renal oncocytoma and renal cell carcinoma Castren, J. P.;Kuopio, T.;Nurmi, M. J.;Collan, Y. U.
  4. Am. J. Physiol. v.262 no.31 Morphometric analysis of the actions of angiotensin Ⅱ on renal arterioles and glomeruli Denton, K. M.;Fennessy, P. A.
  5. Am. J. Physiol. v.268 no.37 Morphometric analysis of effects of angiotensin Ⅱ on glomerular structure in rats Pagtalunan, M. E.;Rasch, R.;Rennke, H. G.;Meyer, T. W.
  6. Anat. Record v.241 Morphometric analysis of the renal veins Satyapal, K. S.;Rambirtch, V.;Pillai, G.
  7. Vertebrates Kardong, K. V.
  8. Am. J. Physiol. v.257 no.26 Molecular events in the organization of renal tubular epithelium : from nephrogenesis to regeneration Bacallo, R.;Fine, L. G.
  9. Kidney Int. v.46 Expression of insulin-like growth factor and binding protein genes during nephrogenesis Matsell, D. G.;Delhanty, P. J. V.;Stepaniuk, O.;Gooddyer, C.;Han, V.K.M.
  10. Laboratory animal medicine Fox JG;Cohen BJ;Loew FM
  11. Anat. Rec. v.228 Effects of maternal bilateral ureteral ligation on the development of the proximal tubule of the kidney in fetal rats : Morphometry and electron microscopic study Okada, T.;Morikawa, Y.
  12. Cell Tissue Res. v.277 Interrelationship of renal vascular development and nephrogenesis Kloth, S.;Aigner, J.;Schmidbauer, A.;Minuth, W.W.
  13. J. Histochem. Cytochem. v.41 no.3 Basement membrane proteoglycans in glomerular morphogenesis : Chondrotin sulfate proteoglycan is temporally and spatially restricted during Development McCarthy, K. J.;Bynum, K.;John, P. L.;Abrahamson, D. R.;Couchman, J. R.