Journal of Life Science (생명과학회지)

Korean Society of Life Science (한국생명과학회)
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Angiotensin Converting Enzyme Inhibitory Activity of Skipjack/Yellow Tuna Cooking Broth

참치 자숙액의 Angiotensin 전환효소 저해작용

  • Yeo, Saeng-Gyu ;
  • Lee, Tae-Gee ;
  • Ahn, Cheol-Woo ;
  • Kim, In-Soo ;
  • Gu, Yeun-Suk ;
  • Park, Yeong-Ho ;
  • Kim, Seon-Bong
  • 여생규 (부산정보대학 레저산업계열) ;
  • 이태기 (부경대학교 식품공학과) ;
  • 안철우 (부산정보대학 레저산업계열) ;
  • 김인수 (경상대학교 식품과학과.해양산업연구소) ;
  • 구연숙 (부경대학교 식품공학과) ;
  • 박영호 (부경대학교 식품공학과) ;
  • 김선봉
  • Published : 1998.06.01
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Abstract

This study was designed to investigate the angiotensin convertin enzyme (ACE) inhibitory activity of skipjack/yellowpin tuna cooking broth. The cooking broth was pretreated with membrane filter (MW cut-off 5,000) to obtain the peptide fraction with ACE inhibition. the crude peptides fractionated with Amberlite IR-120 ($H^{+}$ form and followed by Bio-gel P-2, were separated into nine fractions (T-1 to T-9). The maximum inhibitory activity was observed in the fraction T-4 ($IC_{50}$ value, 0.619mg/ml). The abundant amino acids obtained from active fraction T-4 were phenylaanine, leucine and glutamic acid.

Keywords

References

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