Journal of Life Science (생명과학회지)

Korean Society of Life Science (한국생명과학회)
권호 표지

Searching of Antimicrobial Active compounds from Microalgae

해양 미세조류로부터 항균성 물질의 탐색

  • 주동식 (부경대학교 수산과학대학 식품공학과) ;
  • 이응호 (부경대학교 수산과학대학 식품공학과)
  • Published : 1998.04.01
Download PDF
⟨ Previous Next ⟩

Abstract

As a part of the investigation on useful compounds from microalgae, and its recently that marine planktonic algae have been recognized as potial sources of antibacterial and antifungal substances, we searched for antimicrobial active compounds from the extracts of six microalgae-Lyngbya sp., Tetraselmis sp., Microcystis sp., Chlorella sp., Navicula sp. and Rhalassiosira sp.-treated with several solvents. There were two active species-Lyngbya ap., Teraselmis sp.- in the antimicrobial activity test to bacteria, yeast and molds, especially the activity existed in the extracts by ethyl acetate of supernatants to the microalgae incubatio. and there won’t any activity in two diatoms to the test microorganism.

미세 조류의 항균성 탐색을 위해 베를린 공대 생물공학 연구실에서 좀 균주을 분양받아 독일 현지 연구실에서 연구를 행하였다. 6종의 미세 조류로부터 항균성 시험 시료응 획득하기위해 먼저 배양데 따른 미세 죠류 배양액의 변화를 pH와 균제량으로 관찰하였고, 이를 토대로 시험 시료를 대주중식기와 정기기 두 구간으로 나누어 채취하였다. 얻어진 시료를 균체와 균체 상층액으로 분리하여 각족 용매를 이용하여 분획을 행하여 4-7종의 획분들 얻었거 이들이 가지는 항균 활성을 시험하였다. BGA(blue green algae) 4종류 중에서 Lsp(lyngbya sp.)와 Tsp(Tetraselmis sp.)에서 항균활성이 관측되었는데, 특히 균체외 상층액의 dthyl acetate 추출 획분이 서균과 특히 곰팡이에 대해 강력한 항균 활성이 있는 것으로 확인되었고, 그뢰 2종의 BGA 와 2종의 규조류(diatoms)에서는 항균 활성 획분이 확인되지 않았다.

Keywords

References

  1. Introductory phycology Trainor, F. R.
  2. Arch.Microbiol. v.83 Fatty acid composition and physiological properties of some filamentous blue-green algae Kenyon, C. N.;Rippka, R.;Stainer, R. Y.
  3. J. Phycol. v.18 Accumulation of beta-carotene in halotolerant algae : purificarion and characterization of beta-carotene rich flobules from Dunaliella bardawil(chlorophycea) Ben-Amotz, A.;Katz, A.;Avron, M.
  4. Carbohy. Res. v.72 The extracellular polysaccharides of Porphyridium cruentum and Porphyridium aerugineum Percival, E.;Foyle, R. A. J.
  5. Archives of Microbiology v.112 The cell content and secretion of water solunle viramins in several freshwater algae Aaronson, S.;Dhawale, S. W.;Patni, J.;De Angelis, B.;Frank, O.;Baker, H.
  6. J. Phycol. v.6 The tocopherol, vitamin K, and related isoprenoid quinone composition of a unicellular red algae Antia, N. J.;Desai, I. D.;Romilly, M. J.
  7. Algae Biomass Glycerol, β-carotene and dry algal meal production in commercial cultication of Dunaliella. Ben-Amotz, A.;Avron, M.;G. Shelef(ed.);C. J. Soeder(e.d.)
  8. Marine Natural Products Chemical and Biological Perspectives v.4 Constituents of blue-green algae Moore, R. E.;Scheuer, P. J.(ed.)
  9. Marine algae in Pharmaceutical Science Marine algae and their products and constituents in pharmacy Hoppe, H. A.;Hoppe, H. A.(ed.);Levring, T.(ed.);Tanaka, Y.(ed.)
  10. Proceedings of 4th international coference on Toxic Phytoplankton Screening of marine phytoplankton for antifungal substances. Nakai, H.;Satake, M.;Murata, M.;Yasumoto, T.;E.Graneli(et al.ed)
  11. Nippon Suisan Gakkaishi v.54 Screening of biologically active compounds in microalgae Murakami, M.;Makabe, K.;Okada, S.;Yamaguchi, K.;Konosu, S.
  12. J. Ferment. & Bioeng. v.75 Growth characteristics of S.platensis in Mixotrophic and Heterotrophic conditions Marquez, F. J.;Sasaki, K.;Kakizono, T.;Nishio, N.;Nagai, S.
  13. Boranica Marina v.30 Antibacterial and antifungal properties of some marine diatoms in culture Viso, A. C.;Pesando, D.;Baby, C.
  14. Can. J. of Microbiol. v.12 The antivacterial acrivity of marine planktonic algae Duff, D. C. B.;Bruce, D. L.
  15. The J. of Antibiotics v.21 Goniodomin, a new antibiotic from a dinoflagelate Sharma, G. M.;Michaels, L.;Burkholder, P. R.
  16. J. Nat. Pro. v.47 Antibacterial constituents of the diatom Navicula delognei Findlay, J. A.;Patil, A. D.