동의신경정신과학회지 (Journal of Oriental Neuropsychiatry)

  • 제9권2호
  • /
  • Pages.87-95
  • /
  • 1998
  • /
  • 1226-6396(pISSN)
  • /
  • 2234-4942(eISSN)
대한한방신경정신과학회 (The Korean Society of Oriental Neuropsychiatry)
권호 표지

소음인(少陰人) 소합향원(蘇合香元)이 Stress 생쥐의 뇌(腦) Serotonin 함량(含量)에 미치는 영향(影響)

A Study on Effect of Soeuminsohabhyangwon on the Brain Serotonin contents of Stressed Mice

  • 권순주 (경산대학교 한의과대학 신경정신과학교실) ;
  • 정대규 (경산대학교 한의과대학 신경정신과학교실) ;
  • 김연섭 (경원대학교 한의과대학)
  • Kwen Soon-Ju (Dept. of Oriental Neuropsychiatry, College of Oriental Medicine, Kyung San University) ;
  • Chung Dae-Kyoo (Dept. of Oriental Neuropsychiatry, College of Oriental Medicine, Kyung San University) ;
  • Kim Yun-Sub (College of Oriental Medicine, Kyungwon University)
  • 발행 : 1998.12.30
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초록

This study was aimed to evaluate the anti-stress effect of Soeuminsohabhyangwon on the mice in Cold and Swimming stress.In order to investigate the anti-stress effect of Soeuminsohabhyangwon in Cold and Swimming stressed mice, the serotonin contents were measured by HPLC method in various part of mouse brain The following results were observed. 1. In Cerebral Cortex of Frontal Lobe, the serotonin content was decreased in the Control group as compared with Normal group and the serotonin content was increased in the SHW group as compared with Control group. 2. In hypothalamus, the serotonin content was decreased in the Control group as compared with Normal group and the serotonin content was increased with statistical significance in the SHW group as compared with Control group. 3. In corpus striatum, the serotonin content was decreased in the Control group as compared with Normal group and the serotonin content was increased with statistical significance in the SHW group as compared with Control group. 4. In hippocampus, the serotonin content was decreased in the Control group as compared with Normal group and the serotonin content was increased with statistical significance in the SHW group as compared with control group.Base on the above results, it may be concluded that Soeuminsohabhyangwon are effective to reduce stress.

키워드

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