대한한방내과학회지 (The Journal of Internal Korean Medicine)

대한한방내과학회 (The Society of Internal Korean Medicine)
권호 표지

오공(蜈蚣)이 노령(老齡)에 따른 mouse의 면역(免疫) 기능(機能)에 미치는 영향(影響)

Effects of Scolopendrae corpus on immune response in mice of different ages

  • 김길섭 (동국대학교 한의과대학 내과학교실) ;
  • 서운교 (동국대학교 한의과대학 내과학교실) ;
  • 정지천 (동국대학교 한의과대학 내과학교실)
  • Kim, Gil-Seop (Department of Intenal Medicine, College of Oriental Medicine, Dongguk University) ;
  • Seo, Un-Kyo (Department of Intenal Medicine, College of Oriental Medicine, Dongguk University) ;
  • Jeong, Ji-Cheon (Department of Intenal Medicine, College of Oriental Medicine, Dongguk University)
  • 발행 : 1998.08.30
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초록

To clarify the activating effects of Scolopendrae corpus on immunological function, its effect on primary and secondary antibodies production in mice of various ages was investigated. Scolopendrae corpus increased the number of both antibody producing cells(anti-IgM and anti-IgG producing plaque forming cells, PFC) and phagocytic activity of peritoneal macrophage. Futhermore, these phenomena were significantly increased with aging in mice. Scolopendrae corpus also increased natural killer cell activity concerning to cancer immunology. These results suggest that Scolopendrae corpus markedly increases the reduced activity in the elderly and activates the immune response in senescence mice.

키워드

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