Effects of Acupuncture at Chok-samni(ST36) on Pain in Rats

족삼리(足三里) 침자(鍼刺)가 동통억제(疼痛抑制)에 미치는 영향(影響)

  • Sin Gun-Seong (Dept. of Acupuncture & Moxibustion Oriental Medical College, Won Kwang University) ;
  • Byun Jae-Young (Dept. of Acupuncture & Moxibustion Oriental Medical College, Won Kwang University) ;
  • Ahn Soo-Gi (Dept. of Acupuncture & Moxibustion Oriental Medical College, Won Kwang University) ;
  • Hwang Woo-Jun (Dept. of Acupuncture & Moxibustion Oriental Medical College, Won Kwang University)
  • 신권성 (원광대학교 한의과대학 침구학교실) ;
  • 변재영 (원광대학교 한의과대학 침구학교실) ;
  • 안수기 (원광대학교 한의과대학 침구학교실) ;
  • 황우준 (원광대학교 한의과대학 침구학교실)
  • Published : 1998.12.30

Abstract

The purpose of this study was finding the pain inhibitory effect of acupuncture at ST-36. The pain at dentes incisor was evoked by noxious electric stimulation and EMG changes based on time interval were measured. To do this, the opioid antagonist was administered intraperitoneally. Followings are some of the results. 1. The pain inhibitory effect of acupuncture at ST-36 was 93.82%, 87.00%, 75.30%, 69.76% at 10 20, 30 and 40 minutes respectively. All the data were calculated based on 100% at 0 minute. The effect was very significant at 40 minutes. 2. The continuous effect of acupuncture at ST-36 after taking out the needle was 77.46%, 79.66%, 87.60%, 91.50%, 95.14%, 99.48% at 50, 60, 70, 80, 90 and 100 minutes respectively. The overall continuous effect was shown its maximum 20 minutes after taking out the needle and reached to the initial value at 60 minutes. 3. The pain inhibitory effect following the naloxone administration and acupuncture application ST-36 was 93.44%, 94.58%, 90.80%, 88.04% at 10, 20, 30 and 40 minutes respectively. All values showed similar tendency to the initial data. 4. The continuous effect of acupuncture at ST-36 after taking out the needle which was preceded by the naloxone administration was 91.26%, 91.90%, 92.06%, 93.66%, 94.12%, 93.50% at 50, 60, 70, 80, 90 and 100 minutes respectively. This trend was not a significant fluctuation. It Was concluded that effect of acupuncture at ST-36 was shown in conjunction with secretion of analgesic substance. Therefore it is implied that the acupuncture application will play a major role in treating many diseases with more revelation of scientific acupuncture mechanism. Further studies of acupuncture manipulation are needed in the future based on our study.

Keywords

References

  1. 鍼灸學 楊甲三
  2. 鍼灸學(上) 崔容泰(外)
  3. 黃帝內經素問校注語譯 郭謁春
  4. 韓醫學原論 金完熙
  5. 東醫寶鑑 雜病編 許浚
  6. 靈樞經校釋(下冊) 刺節眞邪篇 河北醫學院
  7. 中醫科學 v.1 中樞5-acyl色amine在鍼刺鎭痛中的作用 韓濟生
  8. 針刺痲醉 v.4 電針對家兎腦內單amine類神經介質的影響 北京市結核病硏究所
  9. 中華醫學雜誌 v.9 脣針鎭痛與5-acyl色amine能神經系統的關係 兪光弟(等)
  10. 中國科學 v.6 鍼刺對內臟驅體反射下行抑制的中樞定位 杜煥基(等)
  11. 生理學報 v.31 no.2 腦內 5-hydroxyl色amine 和인茶분 左鍼刺鎭痛中的作用 金國章(等)
  12. 科學通報 v.4 腦內 5-hydroxyl色amine能神經系統左鍼刺鎭痛中的作用 上海神經遞質與鍼刺鎭痛硏究協作小組
  13. 生理科學進展 v.10 no.4 中樞神經系統中的 P物質 周仲福(等)
  14. Bull. Tokyo Med. Dent. Univ. v.29 Threshold changes of the jaw-opening reflex by the impulses of afferent nerve fibers for conveying electroacupuncture analgesia in rats Kazuo Toda
  15. Bull. Tokyo Med. Dent. Univ. v.27 Effective conditions of electro-acupuncture stimulation for suppressing tooth pulp-evoked jaw-opening reflex in the rat Kazuo Toda
  16. Jap. J. Physiol. v.28 Effects of electro-acupunture on rat jaw opening reflex elicited by tooth pulp stimulation Kazuo Toda
  17. Brain Research Bulletin v.21 Rat hypothalamic arcuate neuron response in electroacupuncture-induced analgesia Michiko Hamba;Kazuo Toda
  18. Bull. Tokyo Med. Dent. Univ. v.27 Diazepam-induced suppression of jaw opening reflex in rats Atsushi Iriki;Etsutaro Ikezono;Kazuo Toda;Hiroyosho Tanaka
  19. American Journal of chinese Medicine no.3 Changes of the jaw opening reflex activity by electro-acupuncture stimulation in rat Kazuo Toda;D.D.S.
  20. Exp. Brain Res. v.80 naloxone-reversible analgesia produced by microstimulation of the arcuate nucleus of the hypothalamus in pentobarbital-anesthetized rats Wang, Q.;Mao, L.M.;Han, J.S.
  21. EXPERIMENTAL NEUROLOGY v.87 Effects the arcuate nucleus of the rat hypothalamus Michiko Hamba;Kazuo Toda
  22. Brain Research v.513 The arcuate nucleus of hypothalamus mediates low but not high frequency electroacupuncture analgesia in rats Qiang Wang;Limin Mao;JIsheng Han
  23. Neuroscience Letters v.142 Influence of electro-acupuncture on the release of substance P and the potential evoked by nucleus caudalis of the rabbit Norifami Yonehara;Takanori Sawada;Hideo Matsuura;Reizo Inoki
  24. Anesth Prog v.38 Effect of Electronic dental anethesia on pain threshold and pain tolerance levels of human teeth subjected to stimulation with an electric pulp tester Gerschman, J.A.;Giebartowski, J.
  25. Brain Research v.549 Electrophysiological analysis of the ascending and descending components of the micturition reflex pathway in the rat Noto, H.;Roppolo, J.R.;Steersr, W.D.
  26. Exp. Neurology v.47 Electro-acupuncture suppression of jawdepression reflex elicited by dentalgia in rabbits David, T.H.;Josep, C.H.;Samuel, H.H.
  27. Pain v.15 Acupuncturre has an analgesic effect in rabbit Han, J.;Zhou, Z.;Xuan, Y.
  28. Brain Research Bulletin v.30 The acupuncture point and its connecting central pathway for producing acupuncture anagesia Takeshige, C.;Oka, K.;Mizuno, T.
  29. Pain v.47 Effect of low and high frequency TENS on Metenkephalin-Arg-Phe and dynorphin A immunoreactivity in human lumber CSF Han, J.S.;Chin, X.L.;Xu, X.J.
  30. Brain Research v.47 Analgesia induced by electroacupuncture of different frequencies is mediated by different types of opioid receptors: another cross-tolerance study Chen, X.H.;Han, J.S.
  31. Amer. J. Chin. Med. v.1 Neurological basis of pain and its possible relationship to acupuncture anesthesia Li, C.L.
  32. Advances in Pain Research and Therapy Acupuncture hyperalgesia : evidence for activation of central control system as mechanism of action Mayer, D.J.;Prece, D.D.;Pafii, A.
  33. Brain Research v.549 Electroacupuncture in rats: evidence for naloxone and naltrexone potentiation of analgesia Bossut, D.F.;Huang, Z.S.;Sun, S.L.
  34. 中國科學 v.4 鍼刺鎭痛的神經生理學基礎 張香桐(等)
  35. 針刺痲醉 家원腦內注射納洛酮對嗚啡鎭痛和指針鎭痛的影向 周仲複(等)
  36. 針刺痲醉 家원中央灰質微量注射納洛동及氣茶內안對針刺鎭痛作用的影向 孫風節(等)
  37. 척추동물의 해부실험 한춘배
  38. SAS를 이용한 통계자료분석 송문섭(외)
  39. 통증의학 오홍근
  40. Pain(1st edition) Fields, H.L.
  41. Pain, Principles of neurology(4th edition) Adams, R.D.;Victor, M.
  42. The management of pain(2nd ed) Bonica, J.J.
  43. J. Neurophysiology v.49 Response properties of thin myelinated fiber in human skin nerves Ariaensen, H.;Gybels, J.;Handwerker, H.O.;Van Hees J.
  44. Pain syndrome in neurology(1st ed) Field, J.L.
  45. Textbook of pain(2nd ed) Wall, P.D.;Melzack, R.
  46. Clinical preventive dentistry v.13 no.6 Leonard G. Horowitx;DMD;MA;MPH;Louise;Kehoe;BDS;MSc;Eli Jacibe;Lic Ac;Dipl Ac(NCCA);MA
  47. Treating feaful dental patients;A patient Management Handbook
  48. Clin. Prev. Dent. v.7 no.1 Progressive relaxation and implosion therapy for dental phobias Horowitz, L.G.
  49. Int. Dent. J. v.28 no.1 New methods of pain measurement and their application to pain control Gracely, R.H.;Dubner, R.;McGrath, P.;Heft, M.
  50. Oral diagnosis Oral Medicine(2nd Ed.) Mitchell, D.F.;Standish, S.M.;Fast, T.B.
  51. Science v.50 Pain mechanisms: a new theory Melzack, R.;Wall, P.
  52. Neurophysiological foundation of pain;The Psychology of pain Melzack, R.;Dennis, S.G.;Sternback, R.A.(ed.)
  53. Pain and Behavioral Medicine, A Cognitive-Behavioral Perspective Rurk, D.;Meichenbaum, D.;Genest, M.
  54. JADA Status report: transcutaneous electrical nerve stimulations(TENS) units in pain control Council on Dental Materials, Instruments and Equipment
  55. Am. J. Acupuncture no.8 The World Health Organization viewpoint on acupuncture Bannerman, R.H.
  56. 대한소아치과학회지 v.23 no.3 전기침이 구강동통에 미치는 영향에 관한 연구 최용성;이창섭;송형근;이상호
  57. Churchill of Acupuncture v.12 no.4 Methods of assessing pain in animals;In Textbook of Pain Dubner, R.;Wall, P.D.;Melzack, R.
  58. Neuroscience v.36 no.1 The thresholds of the jawopening reflex and trigeminal brainstern neurous to tooth-pulp stimulation in acutely and chronically prepared cats Clarke, T.W.
  59. Archs. Oral. Biol. v.14 Reflex jaw opening response to stimulation of periodental mechanoreceptors in the cat Hannamm, A.G.;Mattews, B.
  60. Exp. Neural. v.29 Jaw depression elecited by tooth pulp stimulation Mahan, P.E.;Andersson, K.V.
  61. Pain v.9 Effective needling points for suppressing jaw opening reflex in rat Toda, K.;Suda, H.;Ichioka, M.
  62. J. Pharmacol. Exp. Ther. v.227 no.2 Electrical stimulation at traditional acupuncture sites in periphery produces brain opioid-receptor-mediated antinoception in rats Chen, X.H.;Geller, E.B.;Alder, M.W.
  63. Brain Res. v.104 Changes in burning pain threshold induced by acupuncture in man Croze, S.;Antonietti, C.;Duclauux, R.
  64. Acupunct. Electrother. Res. v.22 no.2 Increased pain threshold following electroacupuncture; analgesia is induced mainly in meridian acupuncture points Farber, P.L.;Tachibana, A.;Campiblia, H.M.
  65. Pharmacol. Toxi. Col. v.22 Neurochemical basis of acupuncture analgesia Han, J.S.;Terenius, L.
  66. 大韓針灸學會誌 v.9 no.1 邊宰煐
  67. 韓醫學大辭典(基礎理論篇) 洪元植(等)
  68. 中國鍼灸治療學 邱茂良
  69. 靈樞經校釋(上冊) 九鍼十二原第一 v.上冊 河北醫學院
  70. 大韓鍼灸學會誌 v.12 no.2 鍼刺로 誘發시킨 經氣變化의 機器的 測定可能性硏究 張敬善(外)
  71. 難經譯釋 中醫醫學名(著)
  72. 類經 張介賓