백작약약침(白芍藥藥鍼)이 백서(白鼠)의 위궤양(胃潰瘍)에 미치는 면역조직화학적(免疫組織化學的) 연구(硏究)

The immunohistochemical studies of Herbal drug-acupuncture of Radix paeoniae lactiflorae on Gastric ulcer induced by HCI-aspirin in Rats

  • 박기현 (경산대학교 한의과대학 침구학교실) ;
  • 한상원 (경산대학교 한의과대학 침구학교실) ;
  • 박재현 (경산대학교 한의과대학 내과학교실)
  • Park Ki-Hyun (Dept. of Acupuncture & Moxibustion, Oriental Medical College, Kyungsan University) ;
  • Han Sang-Won (Dept. of Acupuncture & Moxibustion, Oriental Medical College, Kyungsan University) ;
  • Park Jae-Hyun (Dept. of Internal Medicine, Oriental Medical College, Kyungsan University)
  • 발행 : 1998.12.30

초록

In order to study the immunohistochemical effects of herbal drug-acupuncture of Radix paeoniae lactiflorae on gastric ulcer induced by HCl-aspirin in rats. this experiment was done by herbal drug-acupuncture to Wisu($B_{21}$). Chung-Wan($CV_{12}$), Chok-Samni($S_{36}$) loci to measure histological features of ulcer lesion, the change of numbers of parietal cell, chief celI, gastrin and somatostatin-immunoreactive cell. The obtained results were as follows; 1. The ulcerative lesions of gastric mucosa were decreased to WiSU($B_{21}$) loci followed by Chung-Wan($CV_{12}$) and Chok-Samni($S_{36}$) loci compared to the control groups. 2. In the numbers of parietal cell, the most remarkable decrease was observed to Wisu($B_{21}$) loci followed by Chung-Wan($CV_{12}$) and Chok-Samni($S_{36}$) loci compared to the control groups. 3. In the numbers of chief cell, the most remarkable increase was observed to Wisu($B_{21}$) loci followed by Chung-Wan($CV_{12}$) and Chok-Samni($S_{36}$) loci compared to the control groups. 4. In the numbers of gastrin-immunoreactive cell, the most remarkable decrease was observed to Wiu($B_{21}$) loci followed by Chung-Wan($CV_{12}$) and Chok-Samni($S_{36}$) loci compared to the control groups. 5. In the numbers of somatostatin-immunoreactive cell, the most remarkable decrease was observed to Wisu($B_{21}$) loci followed by Chung-Wan($CV_{12}$) and Chok-Samni($S_{36}$) loci compared to the control groups.

키워드

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