Journal of Pharmaceutical Investigation
- Volume 28 Issue 4
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- Pages.257-266
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- 1998
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- 2093-5552(pISSN)
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- 2093-6214(eISSN)
Dissolution Rate and Bioavailability of Acyclovir, Antiviral Agent, by Cyclodextrin Inclusion Complexation
시클로텍스트린 포접복합체 형성에 의한 항바이러스제 아시클로버의 용출속도 및 생체이용률
- Park, Seung-Hyun (College of Pharmacy, Chung-Ang University) ;
- Kim, Ha-Hyung (College of Pharmacy, Chung-Ang University) ;
- Lee, Kwang-Pyo (College of Pharmacy, Chung-Ang University)
- Published : 1998.12.20
Abstract
To improve the solubility and dissolution rate of acyclovir (ACV), which is low oral bioavailability due to its properties of slight solubility in water and incomplete gastrointestinal absorption, the solid inclusion complexes of ACV with