Journal of Pharmaceutical Investigation
- 제28권4호
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- Pages.257-266
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- 1998
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- 2093-5552(pISSN)
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- 2093-6214(eISSN)
시클로텍스트린 포접복합체 형성에 의한 항바이러스제 아시클로버의 용출속도 및 생체이용률
Dissolution Rate and Bioavailability of Acyclovir, Antiviral Agent, by Cyclodextrin Inclusion Complexation
- Park, Seung-Hyun (College of Pharmacy, Chung-Ang University) ;
- Kim, Ha-Hyung (College of Pharmacy, Chung-Ang University) ;
- Lee, Kwang-Pyo (College of Pharmacy, Chung-Ang University)
- 발행 : 1998.12.20
초록
To improve the solubility and dissolution rate of acyclovir (ACV), which is low oral bioavailability due to its properties of slight solubility in water and incomplete gastrointestinal absorption, the solid inclusion complexes of ACV with