Journal of Pharmaceutical Investigation
- 제28권2호
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- Pages.115-119
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- 1998
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- 2093-5552(pISSN)
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- 2093-6214(eISSN)
세프라딘의 용출에 미치는 결정형의 영향
Effects of Crystal Forms on Dissolution of Cephradin
- Sohn, Young-Taek (College of Pharmacy, Duksung Women's University) ;
- Kim, Ji-Seon (College of Pharmacy, Duksung Women's University)
- 발행 : 1998.06.20
초록
Five polymorphic modifications of Cephradin were prepared by recrystallization from organic solvents. The isolated crystal forms were characterized by differential scanning calorimetry (DSC), thermogravimetric analysis (TGA) and X-ray crystallography powder diffractometry. Modificaition 1 was the most stable form and decomposed at