생약학회지 (Korean Journal of Pharmacognosy)

  • 제29권3호
  • /
  • Pages.231-236
  • /
  • 1998
  • /
  • 0253-3073(pISSN)
  • /
  • 2288-9299(eISSN)
한국생약학회 (The Korean Society of Pharmacognosy)
권호 표지

서양고추냉이 추출물과 분리한 Kaempferol 배당체들의 브로모벤젠 처리 흰쥐에서 in Vitro 지질과산화억제효과

Effect of Methanol Extract and Kaempferol Glycosides from Armoracia rusticana on the Formation of Lipid Peroxide in Bromobenzene-treated Rats In Vitro

  • 허종문 (경상대학교 식품영양학과) ;
  • 이종호 (경상대학교 식품영양학과) ;
  • 최종원 (경성대학교 약학과) ;
  • 황기욱 (경성대학교 약학과) ;
  • 정신교 (경북대학교 식품공학과) ;
  • 김문성 (동아제약) ;
  • 박종철 (순천대학교 한약자원학과 및 유용천연자원연구소)
  • Hur, Jong-Moon (Department of Food and Nutrition, Kyeongsang National University) ;
  • Lee, Jong-Ho (Department of Food and Nutrition, Kyeongsang National University) ;
  • Choi, Jong-Won (College of Pharmacy, Kyongsung University) ;
  • Hwang, Gi-WUk (College of Pharmacy, Kyongsung University) ;
  • Chung, Shin-Kyo (Department of Food Science and Technology, Kyongpook National University) ;
  • Kim, Moon-Sung (Dong-A Pharm. Co.) ;
  • Park, Jong-Cheol (Department Oirental Medicine Resources and Research Institute of Natural Resources, Sunchon National University)
  • 발행 : 1998.09.30
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초록

Three flavonoid glycosides have been isolated from the aerial part of Armoracia rusticana P. (Cruciferae) in Korea and identified by means of spectral analysis as $kaempferol-3-O-{\beta}-D-xylofuranoside(l)$, $kaempferol-3-O-{\beta}-D-galactopyranoside(2)$ and $kaempferol-3-O-{\beta}-D-xylofuranosyl(1\rightarrow2)-b{\beta}-D-galactopyranoside(3)$. When 1 mg/ml of the methanol extract from the aerial part of this plant was added, lipid peroxide formation in the bromobenzene-treated rat liver decreased by 64%. Among the components isolated from title plant, compounds 2 and 3 reduced the formation of lipid peroxide by 16% and 39% respectively at the concentration of ${10}^{-1}$ mg/ml.

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