생약학회지 (Korean Journal of Pharmacognosy)
- 제29권3호
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- Pages.169-172
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- 1998
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- 0253-3073(pISSN)
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- 2288-9299(eISSN)
조구등의 Hyaluronidase 저해물질
Hyaluronidase Inhibitor from Uncariae Ramulus et Uncus
- Jeong, Sei-Joon (College of Pharmacy, Wonkwang University) ;
- Ko, Yong-Seok (College of Pharmacy, Wonkwang University) ;
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Ahn, Nyeon-Hyung
(College of Pharmacy, Wonkwang University) ;
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Kim, Youn-Chul
(College of Pharmacy, Wonkwang University)
- 발행 : 1998.09.30
초록
Hyaluronidase is one of the mucopolysaccharide-splitting enzyme and is related to the permeability of the vascular system and inflammation. An anti-hyaluronidase assay guided fractionation of the methanolic extract of Uncariae Ramulus et Uncus has furnished a pentacyclic triterpene, ursolic acid (compound I). Compound I exhibited hyaluronidase inhibitory activity with