Natural Product Sciences
- Volume 4 Issue 2
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- Pages.88-90
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- 1998
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- 1226-3907(pISSN)
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- 2288-9027(eISSN)
Studies on the Chemical Composition and Antitumor Activity of the Acid Polysaccharide from Alga Sargassum fusiforme
- Qianqun, Gu (Institute of Marine Drugs and Foods, Oean University of Qingdao) ;
- Yuchun, Fang (Institute of Marine Drugs and Foods, Ocean University of Qingdao) ;
- Changyun, Wang (Institute of Marine Drugs and Foods, Ocean University of Qingdao) ;
- Bafang, Li (Institute of Marine Drugs and Foods, Ocean University of Qingdao) ;
- Wenjun, Mao (Institute of Marine Drugs and Foods, Ocean University of Qingdao)
- Published : 1998.06.01
Abstract
An acid polysaccharide (SFP), was extracted from alga Sargassum fusiforme in hot water, was purified by ion exchange chromatography on DEAE-cellulose. The PC, chemical analysis, electrophoresis and IR of SFP indicated that it was a kind of alginate with a mol. wt. of 13,000 and a molar ratio of mannuronic acid to guluronic acid 2.75. Pharmacological tests showed that SFP could prolong the survival duration of mice suffering from ascitic Sarcoma 180 with a rate of life prolongation of 63.44%.