Natural Product Sciences
- Volume 4 Issue 2
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- Pages.72-77
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- 1998
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- 1226-3907(pISSN)
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- 2288-9027(eISSN)
New Assay Method for Surveying Anti-Emetic Compounds from Natural Sources
- Akita, Y. (Department of Pharmacognosy and Phytochemistry, Meiji College of Pharmacy) ;
- Yang, Y. (Department of Pharmacognosy and Phytochemistry, Meiji College of Pharmacy) ;
- Kawai, T. (Department of Pharmacognosy and Phytochemistry, Meiji College of Pharmacy) ;
- Kinoshita, K. (Department of Pharmacognosy and Phytochemistry, Meiji College of Pharmacy) ;
- Koyama, K. (Department of Pharmacognosy and Phytochemistry, Meiji College of Pharmacy) ;
- Takahashi, K. (Department of Pharmacognosy and Phytochemistry, Meiji College of Pharmacy) ;
- Watanabe, K. (Faculty of Pharmaceutical Sciences, Chiba University)
- Published : 1998.06.01
Abstract
The new assay method was developed by using young chicks instead of frogs for screening of anti-emetic compounds from natural sources. Comparing with our previous method using leopard and ranid frogs, the advantages of the new method were not only completely parallel results but also decreasing standard errors. Hinesol and eudesmol were isolated from MeOH extract of Atractylodes lancea rhizome as the anti-emetic principles.