The Korean Journal of Physiology and Pharmacology
- 제2권6호
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- Pages.779-786
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- 1998
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- 1226-4512(pISSN)
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- 2093-3827(eISSN)
Simultaneous HPLC Analysis of Arachidonic Acid Metabolites in Biological Samples with Simple Solid Phase Extraction
- Kim, Hyung-Gun (Department of Pharmacology, College of Medicine, Dankook University) ;
- Huh, Young-Na (Department of Pharmacology, College of Medicine, Dankook University) ;
- Park, Kun-Suk (Department of Pharmacology, College of Medicine, Dankook University)
- 발행 : 1998.12.21
초록
A reversed-phase high-performance liquid chromatogrphy (RP-HPLC) has been developed to analyze the metabolites of arachidonic acid based on the specificities of ultraviolet absorption of these various metabolites and is sensitive to the nanogram level. This procedure makes it possible to extract complex mixtures of eicosanoids efficiently with a single step and to analyze them simultaneously by RP-HPLC from biological samples using octadesylsilyl silica extraction column and
키워드