생물정신의학 (Korean Journal of Biological Psychiatry)
- 제4권1호
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- Pages.74-83
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- 1997
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- 1225-8709(pISSN)
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- 2005-7571(eISSN)
후기발병 정신분열병 환자에서의 뇌자기공명촬영 소견에 관한 연구 : 조기발병 정신분열병, 진행성 정신분열병, 노인성 치매 및 대조군과의 비교
Brain MRI Findings for the Patient with the Late Onset Schizophrenia : Comparison among Patients with the Early Onset Schizophrenia, Progressive Schizophrenia, Senile Dementia and Controls
- 박두성 (인제대학교 의과대학 서울백병원 신경정신과학교실) ;
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이영호
(인제대학교 의과대학 서울백병원 신경정신과학교실) ;
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최영희
(인제대학교 의과대학 서울백병원 신경정신과학교실) ;
- 박영수 (인제대학교 의과대학 서울백병원 신경정신과학교실) ;
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정영조
(인제대학교 의과대학 서울백병원 신경정신과학교실)
- Park, Doo Sung (Department of Neuropsychiatry, College of Medicine, Seoul Paik Hospital, Inje University) ;
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Lee, Young Ho
(Department of Neuropsychiatry, College of Medicine, Seoul Paik Hospital, Inje University) ;
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Choi, Young Hee
(Department of Neuropsychiatry, College of Medicine, Seoul Paik Hospital, Inje University) ;
- Park, Young Soo (Department of Neuropsychiatry, College of Medicine, Seoul Paik Hospital, Inje University) ;
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Chung, Young Cho
(Department of Neuropsychiatry, College of Medicine, Seoul Paik Hospital, Inje University)
- 발행 : 1997.06.25
초록
With increasing tendency of incidence and interest for the late onset schzophrenia, concerns about whether this disorder is etiologically or phenomenogically distinctive entity or not have increased also. To clarify the disease entity of the late onset schzophrenia and the role of structural brain changes in its etiology, authors tried to prove following hypothesis : Are there any evidences of structural brain changes in the lateonset schizophrenia? ; If present, are they not different from those of the early-onset schizophrenia or progressive schizophrenia? ; And are they not different from those of senile dementia? Subjects were 6 patients with the late-onset schizophrenia, 6 patients with the early-onset schizophrenia, 6 patients with progressive schizophrenia, 6 patients with Alzheimer's dementia, and 6 controls. We measured regions of interest of the magnetic resonance images by computer assisted planimetry using the AutoCad and digitizer. Our study results may suggest that the third ventricular enlargement and a reversal of normal difference between left and right temporal lobe and left-right difference in posterior lateral ventricle are common brain pathology for all types of schizophrenia including the late onset schzophrenia. And also suggest that brain structural changes of the late onset schizophrenia are related with neurodevelopmental abnormality rather than degenerative change.
키워드