The Korean Journal of Pain
- 제10권2호
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- Pages.170-178
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- 1997
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- 2005-9159(pISSN)
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- 2093-0569(eISSN)
부인과 수술 후 통증관리에 있어서 프로파세타몰의 모르핀 절감 및 내분비 대사에 대한 효과
The Effect of Postoperative Propacetamol on Acute Pain and Endocrine-Metabolic Response in Gynecological Surgery
- 한태형 (성균관대학교 의과대학, 삼성서울병원 마취과 및 통증관리센터) ;
- 서재완 (성균관대학교 의과대학, 삼성서울병원 마취과 및 통증관리센터) ;
- 신백효 (성균관대학교 의과대학, 삼성서울병원 마취과 및 통증관리센터) ;
- 손종찬 (건국대학교 서울병원 마취과)
- Han, Tae-Hyung (SungKyunKwon University, College of Medicine Samsung Medical Center Department of Anesthesiology and Pain Management Center) ;
- Seo, Jae-Wan (SungKyunKwon University, College of Medicine Samsung Medical Center Department of Anesthesiology and Pain Management Center) ;
- Shin, Baek-Hyo (SungKyunKwon University, College of Medicine Samsung Medical Center Department of Anesthesiology and Pain Management Center) ;
- Son, Jong-Chan (Seoul Branch of Kunkuk University Hospital)
- 발행 : 1997.11.22
초록
Background: The analgesic efficacy and safety of propacetamol, an injectable prodrug of acetoaminophen, in combination with intravenous morphine PCA were studied in 40 patients after gynecological surgery requiring lower abdominal incision. Methods: Using a double-blind, randomized, parallel-group design, the effects of four(every 6 hr) intravenous injections of 2 g propacetamol(=1 g acetoaminophen) were compared with four injections of placebo(PL) immediately after surgery. Efficacy of cumulative dose of morphine and number of boluses requested was assessed over 24 hours by automated recording on the PCA device. It was assessed on pain scores rated on a ten-point verbal scale along with vital signs,
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